Utilize este identificador para referenciar este registo:
https://hdl.handle.net/10316/7944
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Ribeiro, Laura | - |
dc.contributor.author | Veiga, Francisco | - |
dc.date.accessioned | 2009-02-17T10:49:37Z | - |
dc.date.available | 2009-02-17T10:49:37Z | - |
dc.date.issued | 2002 | en_US |
dc.identifier.citation | Journal of Inclusion Phenomena and Macrocyclic Chemistry. 44:1 (2002) 251-256 | en_US |
dc.identifier.uri | https://hdl.handle.net/10316/7944 | - |
dc.description.abstract | Inclusion complexation between ß-cyclodextrin (ß-CD),hydroxypropyl-ß-cyclodextrin (HP-ß-CD), water-solublepolymers (PVP and HPMC) and vinpocetine was studied in aqueous solution and in the solid state.Phase solubility studies were used to evaluate the complexation in aqueous solution at roomtemperature. Stability constants (Kc) of binary and ternary complexes were determined spectrophotometrically. Differential scanning calorimetry (DSC)was used to characterize kneaded, co-evaporated and lyophilised binary and ternary systems.The Kc values obtained were 70.14 M-1 and 35.01 M-1 for vinpocetine-ß-CD and vinpocetine-HP-ß-CD and increased in a range of 17% to 94%by addition of water-soluble polymers. Some preliminary evidences ofinclusion complexation were obtained from DSC suggesting that co-evaporated and lyophilised binary andternary systems were truly inclusion complexes. | en_US |
dc.language.iso | eng | eng |
dc.rights | openAccess | eng |
dc.title | Complexation of Vinpocetine with Cyclodextrins in the Presence or Absence of Polymers. Binary and Ternary Complexes Preparation and Characterization | en_US |
dc.type | article | en_US |
dc.identifier.doi | 10.1023/A:1023069609303 | en_US |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.orcid | 0000-0002-1041-0068 | - |
Aparece nas coleções: | FFUC- Artigos em Revistas Internacionais |
Citações SCOPUSTM
21
Visto em 23/set/2024
Citações WEB OF SCIENCETM
5
21
Visto em 2/out/2024
Visualizações de página 50
565
Visto em 1/out/2024
Downloads 50
688
Visto em 1/out/2024
Google ScholarTM
Verificar
Altmetric
Altmetric
Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.