Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/7596
Title: | Toxicity of MCPA on non-green potato tuber calli | Authors: | Peixoto, Francisco Lopes, M. Madeira, Vítor Vicente, Joaquim |
Issue Date: | 2008 | Abstract: | Abstract Growth of potato tuber calli cells (non-green) is inhibited by 4-chloro-2-methylphenoxyacetic acid (MCPA) as a consequence of perturbation of membrane integrity. MCPA also depresses ATP content with simultaneous increase of ADP and AMP, i.e., the energy charge is severely compromised. Cell redox state is also affected by MCPA, as a function of concentration. Up to 60 µM, MCPA stimulates glutathione reductase and glutathione transferase, whereas superoxide dismutase and catalase activities are not affected. However, 120 µM MCPA inhibits all these activities. Cell death challenged by MCPA is putatively related to disturbance of membrane integrity responsible for mitochondrial uncoupling with decrease of the energy charge and subsequent loss of ions and metabolites. | URI: | https://hdl.handle.net/10316/7596 | DOI: | 10.1007/s11738-008-0207-x | Rights: | openAccess |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais |
Show full item record
SCOPUSTM
Citations
13
checked on Oct 7, 2024
WEB OF SCIENCETM
Citations
5
13
checked on Oct 2, 2024
Page view(s)
377
checked on Oct 15, 2024
Download(s)
250
checked on Oct 15, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.