Utilize este identificador para referenciar este registo: https://hdl.handle.net/10316/5771
Campo DCValorIdioma
dc.contributor.authorSilva, M. Manuel Cruz-
dc.contributor.authorMelo, M. Luísa Sá e-
dc.contributor.authorParolin, Marco-
dc.contributor.authorTessaro, Davide-
dc.contributor.authorRiva, Sergio-
dc.contributor.authorDanieli, Bruno-
dc.date.accessioned2008-09-26T17:41:28Z-
dc.date.available2008-09-26T17:41:28Z-
dc.date.issued2004en_US
dc.identifier.citationTetrahedron: Asymmetry. 15:1 (2004) 21-27en_US
dc.identifier.urihttps://hdl.handle.net/10316/5771-
dc.description.abstractThe enzyme-mediated preparation of enantiomerically or diastereomerically enriched polycyclic cyanohydrins has been investigated. Oxynitrilase-catalyzed cyanurations gave excellent results with the bicyclic aldehydes tested. On the other hand, enantio- or diastereoselective acylation, catalyzed by lipase PS or subtilisin, proved to be a more versatile methodology, giving good results even with sterically hindered polycyclic cyanohydrins. Specifically, the steroidal cyanohydrin derivative 4b was isolated with a 89% de.en_US
dc.description.urihttp://www.sciencedirect.com/science/article/B6THT-4B53Y32-2/1/840d22acaac2079965efb41cc790103een_US
dc.format.mimetypeaplication/PDFen
dc.language.isoengeng
dc.rightsopenAccesseng
dc.titleThe biocatalyzed stereoselective preparation of polycyclic cyanohydrinsen_US
dc.typearticleen_US
dc.identifier.doi10.1016/j.tetasy.2003.11.003-
item.openairetypearticle-
item.fulltextCom Texto completo-
item.languageiso639-1en-
item.grantfulltextopen-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.orcid0000-0002-1938-4150-
Aparece nas coleções:FFUC- Artigos em Revistas Internacionais
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