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Title: Poly(methylene blue) modified electrode sensor for haemoglobin
Authors: Brett, Christopher M. A. 
Inzelt, György 
Kertesz, Vilmos 
Keywords: Poly(methylene blue); Modified electrodes; Haemoglobin; Electrochemical sensor; Batch injection analysis
Issue Date: 1999
Citation: Analytica Chimica Acta. 385:1-3 (1999) 119-123
Abstract: Poly(methylene blue) modified electrodes have been prepared by potential cycling from aqueous electrolyte solution containing methylene blue on glassy carbon substrates. They have been used successfully for the determination of haemoglobin via its electrooxidation at fixed potential using the batch injection analysis technique in which whole blood samples diluted with phosphate or acetate buffer are injected directly over the modified electrode immersed in inert electrolyte. Electrode response is fast, stable, and reproducible. For blood from healthy donors, a good linear correlation was found between the results from the electrochemical injection method and the conventional clinical spectrophotometric measurement after cyanidation. The blood from potentially ill donors showed deviations from the linear correlation suggesting that this may be a good method for detecting haematological problems.
DOI: 10.1016/S0003-2670(98)00808-3
Rights: openAccess
Appears in Collections:FCTUC Química - Artigos em Revistas Internacionais

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