Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/5120
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nunes, Sandra C. C. | - |
dc.contributor.author | Eusébio, M. Ermelinda | - |
dc.contributor.author | Leitão, M. Luísa P. | - |
dc.contributor.author | Redinha, J. S. | - |
dc.date.accessioned | 2008-09-01T15:04:18Z | - |
dc.date.available | 2008-09-01T15:04:18Z | - |
dc.date.issued | 2004 | en_US |
dc.identifier.citation | International Journal of Pharmaceutics. 285:1-2 (2004) 13-21 | en_US |
dc.identifier.uri | https://hdl.handle.net/10316/5120 | - |
dc.description.abstract | Crystallization of pindolol from the melt was studied by differential scanning calorimetry (DSC) and polarized light thermomicroscopy (PLTM) in order to discriminate the polymorphic forms obtained by this method. The crystallization process originates one exothermic signal localized in two different well-defined temperature ranges. Fusion gives rise to overlapped curves, which were analysed by peak-fitting. The polymorphs were identified as the clusters formed with the values obtained for Tpeak of the component curves. Three polymorphic forms were exhibited by pindolol crystallized from the melt. Commercial pindolol presents only two of these forms. | en_US |
dc.description.uri | http://www.sciencedirect.com/science/article/B6T7W-4D98M6B-1/1/3afc552c8d71e8bf5c7a34b60ab20819 | en_US |
dc.format.mimetype | aplication/PDF | en |
dc.language.iso | eng | eng |
dc.rights | openAccess | eng |
dc.subject | Pindolol | en_US |
dc.subject | Recrystallization from melt | en_US |
dc.subject | Polymorphism | en_US |
dc.title | Polymorphism of pindolol, 1-(1H-indol-4-yloxyl)-3-isopropylamino-propan-2-ol | en_US |
dc.type | article | en_US |
uc.controloAutoridade | Sim | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-3060-5719 | - |
crisitem.author.orcid | 0000-0002-5515-7721 | - |
Appears in Collections: | FCTUC Química - Artigos em Revistas Internacionais |
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file61051a6e80a04b50883c0da7c2a0886a.pdf | 509.68 kB | Adobe PDF | View/Open |
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