Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/48362
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Almeida, Jose G. | - |
dc.contributor.author | Preto, Antonio J. | - |
dc.contributor.author | Koukos, Panagiotis I. | - |
dc.contributor.author | Bonvin, Alexandre M. J. J. | - |
dc.contributor.author | Moreira, Irina S. | - |
dc.date.accessioned | 2018-04-17T09:37:26Z | - |
dc.date.issued | 2017-07-15 | - |
dc.identifier.uri | https://hdl.handle.net/10316/48362 | - |
dc.description.abstract | Membrane proteins (MPs) play diverse and important functions in living organisms. They constitute 20% to 30% of the known bacterial, archaean and eukaryotic organisms' genomes. In humans, their importance is emphasized as they represent 50% of all known drug targets. Nevertheless, experimental determination of their three-dimensional (3D) structure has proven to be both time consuming and rather expensive, which has led to the development of computational algorithms to complement the available experimental methods and provide valuable insights. | por |
dc.language.iso | eng | por |
dc.relation | F/00578/2014 | por |
dc.relation | MEMBRANEPROT 659826 | por |
dc.relation | CENTRO-01-0145-FEDER-000008 | por |
dc.relation | TOP-PUNT grant BC.000664.1 | por |
dc.rights | embargoedAccess | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | por |
dc.subject | Algorithms | por |
dc.subject | Computational Biology | por |
dc.subject | Humans | por |
dc.subject | Membrane Proteins | por |
dc.subject | Molecular Dynamics Simulation | por |
dc.subject | Software | por |
dc.title | Membrane proteins structures: A review on computational modeling tools | por |
dc.type | article | - |
degois.publication.firstPage | 2021 | por |
degois.publication.lastPage | 2039 | por |
degois.publication.issue | 10 | por |
degois.publication.title | Biochimica et Biophysica Acta (BBA) - Biomembranes | por |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S000527361730233X?via%3Dihub | por |
dc.peerreviewed | yes | por |
dc.identifier.doi | 10.1016/j.bbamem.2017.07.008 | por |
degois.publication.volume | 1859 | por |
dc.date.embargo | 2019-04-17T09:37:26Z | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0003-4203-2230 | - |
Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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BBA_Postprinting.pdf | 3.94 MB | Adobe PDF | View/Open |
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