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Title: Transdermal iontophoresis—A quantitative and qualitative study
Authors: Ferreira, José Augusto 
Oliveira, Paula de 
Pena, Gonçalo 
Issue Date: 2017
Publisher: Elsevier
Project: info:eu-repo/grantAgreement/FCT/5876/147205/PT 
Serial title, monograph or event: Computers & Mathematics with Applications
Volume: 74
Issue: 10
Abstract: The use of enhancers to increase the drug molecules penetration into target tissues is a usual technique in drug delivery. In transdermal drug delivery, electric fields are often used to increase the drug transport through the skin. In this paper we study a drug delivery mechanism from a reservoir which is in contact with the skin. We assume that the drug transport in the coupled system is enhanced by a small electric field that induces a convective field. We establish energy estimates for the coupled system and we propose a semi-analytical discrete coupled model that mimics the continuous model. The qualitative behaviour of the system is illustrated.
DOI: 10.1016/j.camwa.2017.07.001
Rights: embargoedAccess
Appears in Collections:I&D CMUC - Artigos em Revistas Internacionais

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