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Title: Cardiovascular risk analysis by means of pulse morphology and clustering methodologies
Authors: Almeida, Vânia G. 
Borba, J. 
Pereira, H. Catarina 
Pereira, Tânia 
Correia, Carlos 
Pêgo, Mariano 
Cardoso, João 
Keywords: Arterial stiffness; Pulse wave analysis; Risk scores; Clustering analysis
Issue Date: Nov-2014
Publisher: Elsevier
Citation: ALMEIDA, Vânea G. [et. al] - Cardiovascular risk analysis by means of pulse morphology and clustering methodologies. "Computer Methods and Programs in Biomedicine". ISSN 0169-2607. Vol. 117 Nº. 2 (2014) p. 257–266
Serial title, monograph or event: Computer Methods and Programs in Biomedicine
Volume: 117
Issue: 2
Abstract: The purpose of this study was the development of a clustering methodology to deal with arterial pressure waveform (APW) parameters to be used in the cardiovascular risk assessment. One hundred sixteen subjects were monitored and divided into two groups. The first one (23 hypertensive subjects) was analyzed using APW and biochemical parameters, while the remaining 93 healthy subjects were only evaluated through APW parameters. The expectation maximization (EM) and k-means algorithms were used in the cluster analysis, and the risk scores (the Framingham Risk Score (FRS), the Systematic COronary Risk Evaluation (SCORE) project, the Assessing cardiovascular risk using Scottish Intercollegiate Guidelines Network (ASSIGN) and the PROspective Cardiovascular Münster (PROCAM)), commonly used in clinical practice were selected to the cluster risk validation. The result from the clustering risk analysis showed a very significant correlation with ASSIGN (r = 0.582, p < 0.01) and a significant correlation with FRS (r = 0.458, p < 0.05). The results from the comparison of both groups also allowed to identify the cluster with higher cardiovascular risk in the healthy group. These results give new insights to explore this methodology in future scoring trials.
ISSN: 0169-2607
DOI: 10.1016/j.cmpb.2014.06.010
Rights: openAccess
Appears in Collections:FCTUC Física - Artigos em Revistas Internacionais

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