Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/116126
DC FieldValueLanguage
dc.contributor.authorPitrez, Patrícia R.-
dc.contributor.authorMonteiro, Luís M.-
dc.contributor.authorBorgogno, Oliver-
dc.contributor.authorNissan, Xavier-
dc.contributor.authorMertens, Jerome-
dc.contributor.authorFerreira, Lino-
dc.date.accessioned2024-08-19T11:26:51Z-
dc.date.available2024-08-19T11:26:51Z-
dc.date.issued2024-02-28-
dc.identifier.issn2041-1723pt
dc.identifier.urihttps://hdl.handle.net/10316/116126-
dc.description.abstractThe design of human model systems is highly relevant to unveil the underlying mechanisms of aging and to provide insights on potential interventions to extend human health and life span. In this perspective, we explore the potential of 2D or 3D culture models comprising human induced pluripotent stem cells and transdifferentiated cells obtained from aged or age-related disorder-affected donors to enhance our understanding of human aging and to catalyze the discovery of anti-aging interventions.pt
dc.language.isoengpt
dc.publisherNature Researchpt
dc.relationinfo:eu-repo/grantAgreement/FCT/PTDC/BTM-SAL/5174/2020pt
dc.relationinfo:eu-repo/grantAgreement/HE/101087071/CHAngeingpt
dc.relationinfo:eu-repo/grantAgreement/FCT/2022.07615.PTDCpt
dc.relationinfo:eu-repo/grantAgreement/H2020/952266/RESETageingpt
dc.relationinfo:eu-repo/grantAgreement/HE/101129812/REGENERARpt
dc.relationinfo:eu-repo/grantAgreement/HE/101080229/DREAMSpt
dc.rightsopenAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt
dc.subject.meshHumanspt
dc.subject.meshAgedpt
dc.subject.meshAgingpt
dc.subject.meshCellular Reprogrammingpt
dc.subject.meshLongevitypt
dc.subject.meshInduced Pluripotent Stem Cellspt
dc.titleCellular reprogramming as a tool to model human aging in a dishpt
dc.typearticle-
degois.publication.firstPage1816pt
degois.publication.issue1pt
degois.publication.titleNature Communicationspt
dc.relation.publisherversionhttps://www.nature.com/articles/s41467-024-46004-5pt
dc.peerreviewedyespt
dc.identifier.doi10.1038/s41467-024-46004-5pt
degois.publication.volume15pt
dc.date.embargo2024-02-28*
uc.date.periodoEmbargo0pt
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.cerifentitytypePublications-
item.openairetypearticle-
crisitem.project.grantnoConnected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function-
crisitem.project.grantnoRESEarch for healThy AGEING-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.researchunitCNC - Center for Neuroscience and Cell Biology-
crisitem.author.orcid0000-0002-3116-0723-
crisitem.author.orcid0000-0001-8985-9302-
Appears in Collections:FMUC Medicina - Artigos em Revistas Internacionais
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