Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/115070
Title: BI-REAL: A 12-session DBT skills group intervention adapted for bipolar disorder - A feasibility randomised pilot trial
Authors: Azevedo, Julieta Martins 
Swales, Michaela
Carreiras, Diogo 
Guiomar, Raquel 
Macedo, António 
Castilho, Paula 
Keywords: Bipolar disorder; DBT-ST; Skills training; Emotion regulation; Recovery; Pilot RCT
Issue Date: 13-Apr-2024
Publisher: Elsevier
Project: FCT - SFRH/BD/130116/2017 
FCT - SFRH/BD/5099/2020 
Serial title, monograph or event: Journal of Affective Disorders
Volume: 356
Abstract: International guidelines endorse psychological treatment for Bipolar Disorder (BD); however, the absence of a recognised gold-standard intervention requires further research. A Dialectical Behaviour Therapy (DBT) skills group intervention with 12 sessions was developed. This pilot randomised controlled trial (RCT) aims to evaluate the feasibility, acceptability, and outcomes variance of Bi-REAL – Respond Effectively, Assertively, and Live mindfully, tailored for individuals with BD, in preparation for a future RCT. Methods: 52 participants (female = 62.7 %; mean age = 43.2 ± 11.1) with BD were randomised by blocks to either the experimental group (EG; n = 26; Bi-REAL + Treatment as Usual, TAU) receiving 12 weekly 90-minutes sessions, or the control group (CG; n = 26, TAU). Feasibility and acceptability were assessed with a multimethod approach (qualitative interviews, semi-structured clinical interviews and a battery of self-report questionnaires – candidate main outcomes Bipolar Recovery Questionnaire (BRQ) and brief Quality of Life for Bipolar Disorder (QoL.BD)). All participants were evaluated at baseline (T0), post-intervention (T1) and 3-month follow-up (T2). Results: Acceptability was supported by participants’ positive feedback and ratings of the sessions and programme overall, as well as the treatment attendance (86.25 % of sessions attended). The trial overall retention rate was 74.5 %, with CG having a higher dropout rate across the 3-timepoints (42.31 %). A significant Time × Group interaction effect was found for BRQ and QoL.BD favouring the intervention group (p < .05). Limitations: The assessors were not blind at T1 (only at T2). Recruitment plan was impacted due to COVID-19 restrictions and replication is questionable. High attrition rates in the CG. Conclusions: The acceptability of Bi-REAL was sustained, and subsequent feasibility testing will be necessary to establish whether the retention rates of the overall trial improve and if feasibility is confirmed, before progressing to a definitive trial.
URI: https://hdl.handle.net/10316/115070
ISSN: 01650327
DOI: 10.1016/j.jad.2024.04.033
Rights: openAccess
Appears in Collections:I&D CIBIT - Artigos em Revistas Internacionais
FMUC Medicina - Artigos em Revistas Internacionais
I&D CINEICC - Artigos em Revistas Internacionais
FPCEUC - Artigos em Revistas Internacionais

Show full item record

Page view(s)

13
checked on May 29, 2024

Download(s)

11
checked on May 29, 2024

Google ScholarTM

Check

Altmetric

Altmetric


This item is licensed under a Creative Commons License Creative Commons