Please use this identifier to cite or link to this item:
Title: Three-Dimensional Impression of Biomaterials for Alveolar Graft: Scoping Review
Authors: Francisco, Inês 
Basílio, Ângela 
Ribeiro, Madalena Prata 
Nunes, Catarina 
Travassos, Raquel 
Marques, Filipa 
Pereira, Flávia 
Paula, Anabela Baptista 
Carrilho, Eunice 
Marto, Carlos Miguel 
Vale, Francisco 
Keywords: alveolar bone grafting; bone regeneration; bone substitutes; printing; three-dimensional
Issue Date: 29-Jan-2023
Publisher: MDPI
Serial title, monograph or event: Journal of Functional Biomaterials
Volume: 14
Issue: 2
Abstract: Craniofacial bone defects are one of the biggest clinical challenges in regenerative medicine, with secondary autologous bone grafting being the gold-standard technique. The development of new three-dimensional matrices intends to overcome the disadvantages of the gold-standard method. The aim of this paper is to put forth an in-depth review regarding the clinical efficiency of available 3D printed biomaterials for the correction of alveolar bone defects. A survey was carried out using the following databases: PubMed via Medline, Cochrane Library, Scopus, Web of Science, EMBASE, and gray literature. The inclusion criteria applied were the following: in vitro, in vivo, ex vivo, and clinical studies; and studies that assessed bone regeneration resorting to 3D printed biomaterials. The risk of bias of the in vitro and in vivo studies was performed using the guidelines for the reporting of pre-clinical studies on dental materials by Faggion Jr and the SYRCLE risk of bias tool, respectively. In total, 92 publications were included in the final sample. The most reported three-dimensional biomaterials were the PCL matrix, β-TCP matrix, and hydroxyapatite matrix. These biomaterials can be combined with different polymers and bioactive molecules such as rBMP-2. Most of the included studies had a high risk of bias. Despite the advances in the research on new three-dimensionally printed biomaterials in bone regeneration, the existing results are not sufficient to justify the application of these biomaterials in routine clinical practice.
ISSN: 2079-4983
DOI: 10.3390/jfb14020076
Rights: openAccess
Appears in Collections:I&D CIBB - Artigos em Revistas Internacionais
I&D ICBR - Artigos em Revistas Internacionais
FMUC Medicina - Artigos em Revistas Internacionais

Show full item record

Page view(s)

checked on May 29, 2024


checked on May 29, 2024

Google ScholarTM




This item is licensed under a Creative Commons License Creative Commons