Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/113454
Title: | Chitosan Nanoparticles-Based Cancer Drug Delivery: Application and Challenges | Authors: | Sachdeva, Bhuvi Sachdeva, Punya Negi, Arvind Ghosh, Shampa Han, Sungsoo Dewanjee, Saikat Jha, Saurabh Kumar Bhaskar, Rakesh Sinha, Jitendra Kumar Paiva-Santos, Ana Cláudia Jha, Niraj Kumar Kesari, Kavindra Kumar |
Keywords: | nanoparticles; chitosan; chitin; polysaccharides; nanocarriers; anticancer agents | Issue Date: | 28-Mar-2023 | Publisher: | MDPI | Serial title, monograph or event: | Marine Drugs | Volume: | 21 | Issue: | 4 | Abstract: | Chitin is the second most abundant biopolymer consisting of N-acetylglucosamine units and is primarily derived from the shells of marine crustaceans and the cell walls of organisms (such as bacteria, fungi, and algae). Being a biopolymer, its materialistic properties, such as biodegradability, and biocompatibility, make it a suitable choice for biomedical applications. Similarly, its deacetylated derivative, chitosan, exhibits similar biocompatibility and biodegradability properties, making it a suitable support material for biomedical applications. Furthermore, it has intrinsic material properties such as antioxidant, antibacterial, and antitumor. Population studies have projected nearly 12 million cancer patients across the globe, where most will be suffering from solid tumors. One of the shortcomings of potent anticancer drugs is finding a suitable cellular delivery material or system. Therefore, identifying new drug carriers to achieve effective anticancer therapy is becoming essential. This paper focuses on the strategies implemented using chitin and chitosan biopolymers in drug delivery for cancer treatment. | URI: | https://hdl.handle.net/10316/113454 | ISSN: | 1660-3397 | DOI: | 10.3390/md21040211 | Rights: | openAccess |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Chitosan-NanoparticlesBased-Cancer-Drug-Delivery-Application-and-ChallengesMarine-Drugs.pdf | 1.4 MB | Adobe PDF | View/Open |
Page view(s)
72
checked on Oct 9, 2024
Download(s)
79
checked on Oct 9, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License