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https://hdl.handle.net/10316/113331
Title: | Spectral CT: Current Liver Applications | Authors: | Borges, Ana P Antunes, Célia Alves, Filipe Caseiro |
Keywords: | dual-energy CT; spectral CT; liver disease; pancreatic disease; dual-source CT; fast kVp switching; dual-layer detector CT; split-filter; image quality; photon counting | Issue Date: | 9-May-2023 | Publisher: | MDPI | Serial title, monograph or event: | Diagnostics | Volume: | 13 | Issue: | 10 | Abstract: | Using two different energy levels, dual-energy computed tomography (DECT) allows for material differentiation, improves image quality and iodine conspicuity, and allows researchers the opportunity to determine iodine contrast and radiation dose reduction. Several commercialized platforms with different acquisition techniques are constantly being improved. Furthermore, DECT clinical applications and advantages are continually being reported in a wide range of diseases. We aimed to review the current applications of and challenges in using DECT in the treatment of liver diseases. The greater contrast provided by low-energy reconstructed images and the capability of iodine quantification have been mostly valuable for lesion detection and characterization, accurate staging, treatment response assessment, and thrombi characterization. Material decomposition techniques allow for the non-invasive quantification of fat/iron deposition and fibrosis. Reduced image quality with larger body sizes, cross-vendor and scanner variability, and long reconstruction time are among the limitations of DECT. Promising techniques for improving image quality with lower radiation dose include the deep learning imaging reconstruction method and novel spectral photon-counting computed tomography. | URI: | https://hdl.handle.net/10316/113331 | ISSN: | 2075-4418 | DOI: | 10.3390/diagnostics13101673 | Rights: | openAccess |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Spectral-CT-Current-Liver-ApplicationsDiagnostics.pdf | 14.04 MB | Adobe PDF | View/Open |
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