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dc.contributor.authorFerreira, J. A.-
dc.contributor.authorOliveira, P. de-
dc.contributor.authorSilva, P. M. da-
dc.contributor.authorCarreira, A.-
dc.contributor.authorGil, H.-
dc.contributor.authorMurta, J. N.-
dc.identifier.citationPré-Publicações DMUC. 09-20 (2009)en_US
dc.description.abstractThis paper focuses on ophthalmic drug release from a loaded copolymer: the drug is dispersed in the polymeric matrix and entrapped in particles. The copolymer is based in 2-hydroxyethyl methacrylate co-methacrylic acid and silicone is used to prepare the loaded particles. A mathematical model to simulate the drug release is proposed and a qualitative analysis is performed. Experimental results are compared with simulation results. Contact lens made from the presented copolymer are expected to deliver drug at therapeutical levels for a few days.en_US
dc.description.sponsorshipProject PTDC/MAT/74548/2006en_US
dc.publisherCentro de Matemática da Universidade de Coimbraen_US
dc.subjectOphthalmic drug deliveryen_US
dc.subjectContact lensesen_US
dc.subjectReaction-diffusion equationen_US
dc.subjectQualitative behaviouren_US
dc.subjectNumerical simulationen_US
dc.subjectExperimental resultsen_US
dc.titleSustained drug released from contact lensen_US
item.fulltextCom Texto completo-
item.grantfulltextopen- de Medicina, Universidade de Coimbra-
Appears in Collections:FMUC Medicina - Vários
FCTUC Eng.Química - Vários
FCTUC Matemática - Vários
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