Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/11167
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dc.contributor.authorFerreira, J. A.-
dc.contributor.authorOliveira, P. de-
dc.contributor.authorSilva, P. M. da-
dc.contributor.authorCarreira, A.-
dc.contributor.authorGil, H.-
dc.contributor.authorMurta, J. N.-
dc.date.accessioned2009-08-26T13:27:38Z-
dc.date.available2009-08-26T13:27:38Z-
dc.date.issued2009-
dc.identifier.citationPré-Publicações DMUC. 09-20 (2009)en_US
dc.identifier.urihttp://hdl.handle.net/10316/11167-
dc.description.abstractThis paper focuses on ophthalmic drug release from a loaded copolymer: the drug is dispersed in the polymeric matrix and entrapped in particles. The copolymer is based in 2-hydroxyethyl methacrylate co-methacrylic acid and silicone is used to prepare the loaded particles. A mathematical model to simulate the drug release is proposed and a qualitative analysis is performed. Experimental results are compared with simulation results. Contact lens made from the presented copolymer are expected to deliver drug at therapeutical levels for a few days.en_US
dc.description.sponsorshipProject PTDC/MAT/74548/2006en_US
dc.language.isoengen_US
dc.publisherCentro de Matemática da Universidade de Coimbraen_US
dc.rightsopenAccesseng
dc.subjectOphthalmic drug deliveryen_US
dc.subjectContact lensesen_US
dc.subjectp-(HEMA/MAA)en_US
dc.subjectReaction-diffusion equationen_US
dc.subjectQualitative behaviouren_US
dc.subjectNumerical simulationen_US
dc.subjectExperimental resultsen_US
dc.titleSustained drug released from contact lensen_US
dc.typepreprinten_US
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextCom Texto completo-
crisitem.author.deptFaculdade de Medicina, Universidade de Coimbra-
crisitem.author.researchunitCNC.IBILI-
crisitem.author.orcid0000-0001-8926-5176-
Appears in Collections:FMUC Medicina - Vários
FCTUC Eng.Química - Vários
FCTUC Matemática - Vários
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