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https://hdl.handle.net/10316/111170| Title: | N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease | Authors: | Hofmanova, Tereza Marques, Carolina García-Sosa, Alfonso T. López, Óscar Leitzbach, Luisa Carreiro, Elisabete P. González-Bakker, Aday Puerta, Adrián Stark, Holger Padrón, José M. Fernández-Bolaños, José G. Burke, Anthony J. |
Keywords: | Oxindole; Alzheimer’s disease; Cholinesterase; Mono-amine oxidase; Molecular docking; STD-NMR; Continuous live cell imaging | Issue Date: | 2023 | Publisher: | Elsevier | Project: | We acknowledge the Fundaç˜ao para a Ciˆencia e a Tecnologia (FCT) for funding through the strategic project to LAQV-REQUIMTE (FCT/ MCTES; UIDB/50006/2020|UIDP/50006/2020). O.L. and J.G.F.-B. thank Grant PID2020-116460RB-I00 funded by MCIN/AEI/10.13039/ 501100011033 and Junta de Andalucía (FQM-134) for financial support. A.T.G.-S. thanks to the Estonian Research Council (PRG1509) for funding. A.G.-B., A.P. and J.M.P. thank the Spanish Government (Project PID2021-123059OB-I00 funded by MCIN/AEI /10.13039/ 501100011033 / FEDER, UE). A.P. thanks the EU Social Fund (FSE) and the Canary Islands ACIISI for a predoctoral grant TESIS2020010055. A. G.-B. thanks the Asociaci´on Espa˜nola Contra el C´ancer (AECC) for a predoctoral grant. We are extremely grateful to COST Action 15135, a Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig). Also, TH thanks both the University of Hradec Kr´alov´e (Faculty of Science) and the Erasmus + program for a travel grant (2019-1-CZ01-KA103-060058) | Serial title, monograph or event: | Results in Chemistry | Volume: | 6 | URI: | https://hdl.handle.net/10316/111170 | ISSN: | 22117156 | DOI: | 10.1016/j.rechem.2023.101032 | Rights: | openAccess |
| Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais FCTUC Química - Artigos em Revistas Internacionais FFUC- Artigos em Revistas Internacionais |
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| N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives Potential Biological Activities against Alzheimer's Disease.pdf | 3.84 MB | Adobe PDF | View/Open |
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