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Title: 6-Methyl-ideneandrost-4-ene-3,17-dione
Authors: Andrade, L. C. R. 
Almeida, M. J. M. 
Roleira, F. M. Fernandes 
Varela, Carla Lopes 
Tavares da Silva, E.J. 
Keywords: single-crystal X-ray study; T = 293 K; mean (C–C) = 0.004 A°; R factor = 0.040; wR factor = 0.100; data-to-parameter ratio = 9.8
Issue Date: 1-Apr-2012
Publisher: International Union of Crystallography
Project: project PEst-C/FIS/UI0036/2011 
Serial title, monograph or event: Acta Crystallographica Section E: Structure Reports Online
Volume: 68
Issue: Pt 4
Abstract: In the title compound, C(20)H(26)O(2), which is the 6-methyl-ene derivative of androstenedione and a synthetic percursor of exemestane, the steroid A ring approximates to a sofa (or envelope) conformation, with the methyl-ene group adjacent to the link to the B ring lying out of the plane of the other atoms. The B and C rings have slightly flattened chair conformations and the D ring is an envelope, with the CH group forming the flap. In the crystal, mol-ecules are linked by two distinct C-H⋯O hydrogen bonds, involving acidic H atoms close to C=C and C=O double bonds.
ISSN: 1600-5368
DOI: 10.1107/S1600536812013207
Rights: openAccess
Appears in Collections:FFUC- Artigos em Revistas Internacionais
FCTUC Física - Artigos em Revistas Internacionais

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