Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/109708
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rosa, Andreia Martins | - |
dc.contributor.author | Silva, Maria Fátima | - |
dc.contributor.author | Ferreira, Sónia | - |
dc.contributor.author | Murta, Joaquim | - |
dc.contributor.author | Castelo-Branco, Miguel | - |
dc.date.accessioned | 2023-10-23T10:52:40Z | - |
dc.date.available | 2023-10-23T10:52:40Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2314-6133 | pt |
dc.identifier.issn | 2314-6141 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/109708 | - |
dc.description.abstract | Neuroplasticity refers to the ability of the brain to reorganize the function and structure of its connections in response to changes in the environment. Adult human visual cortex shows several manifestations of plasticity, such as perceptual learning and adaptation, working under the top-down influence of attention. Plasticity results from the interplay of several mechanisms, including the GABAergic system, epigenetic factors, mitochondrial activity, and structural remodeling of synaptic connectivity. There is also a downside of plasticity, that is, maladaptive plasticity, in which there are behavioral losses resulting from plasticity changes in the human brain. Understanding plasticity mechanisms could have major implications in the diagnosis and treatment of ocular diseases, such as retinal disorders, cataract and refractive surgery, amblyopia, and in the evaluation of surgical materials and techniques. Furthermore, eliciting plasticity could open new perspectives in the development of strategies that trigger plasticity for better medical and surgical outcomes. | pt |
dc.language.iso | eng | pt |
dc.publisher | Hindawi | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject.mesh | GABAergic Neurons | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | Learning | pt |
dc.subject.mesh | Synapses | pt |
dc.subject.mesh | Visual Cortex | pt |
dc.subject.mesh | Adaptation, Physiological | pt |
dc.subject.mesh | Neuronal Plasticity | pt |
dc.title | Plasticity in the human visual cortex: an ophthalmology-based perspective | pt |
dc.type | article | - |
degois.publication.firstPage | 568354 | pt |
degois.publication.lastPage | 13 | pt |
degois.publication.title | BioMed Research International | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1155/2013/568354 | pt |
degois.publication.volume | 2013 | pt |
dc.date.embargo | 2013-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.fulltext | Com Texto completo | - |
item.cerifentitytype | Publications | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CIBIT - Coimbra Institute for Biomedical Imaging and Translational Research | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CIBIT - Coimbra Institute for Biomedical Imaging and Translational Research | - |
crisitem.author.orcid | 0000-0001-6608-3353 | - |
crisitem.author.orcid | 0000-0002-3270-7575 | - |
crisitem.author.orcid | 0000-0001-8926-5176 | - |
crisitem.author.orcid | 0000-0003-4364-6373 | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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Plasticity-in-the-human-visual-cortex-An-ophthalmologybased-perspectiveBioMed-Research-International.pdf | 1.61 MB | Adobe PDF | View/Open |
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