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https://hdl.handle.net/10316/108289
Title: | Vitamin D and Age-Related Macular Degeneration | Authors: | Layana, Alfredo Garcia Minnella, Angelo Maria Garhöfer, Gerhard Aslam, Tariq Holz, Frank G Leys, Anita Silva, Rufino Delcourt, Cécile Souied, Eric Seddon, Johanna M. |
Keywords: | vitamin D; age-related macular degeneration; inflammation; angiogenesis | Issue Date: | 13-Oct-2017 | Publisher: | MDPI | Project: | Laboratoires Théa, France | Serial title, monograph or event: | Nutrients | Volume: | 9 | Issue: | 10 | Abstract: | In recent years, the relationship between vitamin D and health has received growing attention from the scientific and medical communities. Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD). Its active metabolite, 1α,25-dihydoxy vitamin D, acts as a modulator of cell proliferation, differentiation and apoptosis, and cumulative data from experimental and observational studies suggest that relatively a lower vitamin D status could be a potential risk factor for the development of early and/or late AMD. Herein, we made a narrative review of the mechanisms linking a potential role of vitamin D with the current concepts of AMD pathophysiology. | URI: | https://hdl.handle.net/10316/108289 | ISSN: | 2072-6643 | DOI: | 10.3390/nu9101120 | Rights: | openAccess |
Appears in Collections: | I&D IBILI - Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
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Vitamin-D-and-agerelated-macular-degenerationNutrients.pdf | 1.16 MB | Adobe PDF | View/Open |
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