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https://hdl.handle.net/10316/106837
Title: | Fertility preservation with successful pregnancy outcome in a patient with transplanted heart and non-Hodgkin's lymphoma - a case report | Authors: | Pais, Ana Sofia Guerra, Nuno Couto, Daniela Sousa, Ana Paula Almeida-Santos, Teresa |
Keywords: | Pregnancy; Oocyte cryopreservation; Pelvic irradiation; Heart transplant | Issue Date: | 19-Nov-2019 | Publisher: | Springer Nature | Serial title, monograph or event: | BMC Pregnancy and Childbirth | Volume: | 19 | Issue: | 1 | Abstract: | Background: Fertility preservation must be discussed with reproductive age women before cancer treatment. Heart transplantation raises complex issues in pregnancy. Pregnancy in a heart transplant woman after pelvic irradiation involves close multidisciplinary follow-up to avoid complications in the mother and the foetus. We report the first live birth in a heart transplant woman after pelvic irradiation, chemotherapy and fertility preservation. Case presentation: A 36-year-old heart transplant woman with pelvic non-Hodgkin lymphoma spared her fertility, with cryopreservation of oocytes and embryos, before chemotherapy and pelvic irradiation. After multidisciplinary discussion and pre-conception evaluation, pregnancy was achieved. A close follow-up by a multidisciplinary team allowed a normal pregnancy without maternal or foetal complications and the delivery of a healthy infant. Conclusions: Achieving pregnancy in heart transplant women with iatrogenic ovarian failure after oncologic treatment including pelvic irradiation is possible and can be successful. Careful and close surveillance by a multidisciplinary team is mandatory due to increased risk of maternal and foetal complications. | URI: | https://hdl.handle.net/10316/106837 | ISSN: | 1471-2393 | DOI: | 10.1186/s12884-019-2587-x | Rights: | openAccess |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais I&D CNC - Artigos em Revistas Internacionais |
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