Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105858
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Petkovic, Marija | - |
dc.contributor.author | Sørensen, Anja Elaine | - |
dc.contributor.author | Leal, Ermelindo Carreira | - |
dc.contributor.author | Carvalho, Eugenia | - |
dc.contributor.author | Dalgaard, Louise Torp | - |
dc.date.accessioned | 2023-03-13T09:58:48Z | - |
dc.date.available | 2023-03-13T09:58:48Z | - |
dc.date.issued | 2020-10-02 | - |
dc.identifier.issn | 2073-4409 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105858 | - |
dc.description.abstract | Wound healing is a complex biological process that is impaired under diabetes conditions. Chronic non-healing wounds in diabetes are some of the most expensive healthcare expenditures worldwide. Early diagnosis and efficacious treatment strategies are needed. microRNAs (miRNAs), a class of 18-25 nucleotide long RNAs, are important regulatory molecules involved in gene expression regulation and in the repression of translation, controlling protein expression in health and disease. Recently, miRNAs have emerged as critical players in impaired wound healing and could be targets for potential therapies for non-healing wounds. Here, we review and discuss the mechanistic background of miRNA actions in chronic wounds that can shed the light on their utilization as specific wound healing biomarkers. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | Danish Diabetes Academy (DDA) supported by the Novo Nordisk Foundation and from Roskilde University | pt |
dc.relation | POCI-01-0145-FEDER-007440 | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | Healthy Aging 2020-CENTRO-01-0145-FEDER-000012-N2323 | pt |
dc.relation | DL57/2016/CP1448/CT0024, NIGMS-P20GM109096, 5P30-AG028718 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | diabetic wound healing | pt |
dc.subject | chronic wounds | pt |
dc.subject | inflammation | pt |
dc.subject | proliferation | pt |
dc.subject | remodeling | pt |
dc.subject | tissue and circulating microRNAs | pt |
dc.subject | tissue regeneration | pt |
dc.subject.mesh | Diabetes Mellitus | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | MicroRNAs | pt |
dc.subject.mesh | Wound Healing | pt |
dc.title | Mechanistic Actions of microRNAs in Diabetic Wound Healing | pt |
dc.type | article | - |
degois.publication.firstPage | 2228 | pt |
degois.publication.issue | 10 | pt |
degois.publication.title | Cells | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/cells9102228 | pt |
degois.publication.volume | 9 | pt |
dc.date.embargo | 2020-10-02 | * |
uc.date.periodoEmbargo | 0 | pt |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.project.grantno | Center for Innovative Biomedicine and Biotechnology - CIBB | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0003-1748-9861 | - |
crisitem.author.orcid | 0000-0001-6264-3632 | - |
Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais IIIUC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Mechanistic-Actions-of-microRNAs-in-Diabetic-Wound-HealingCells.pdf | 36.74 MB | Adobe PDF | View/Open |
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