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https://hdl.handle.net/10316/105854| Title: | Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies | Authors: | Catarata, Maria Joana Medeiros, Rui Oliveira, Maria José Pêgo, Alice Frade, João Gonçalo Martins, Maria de Fátima Cordeiro, Carlos Robalo Herth, Felix J. F. Thomas, Michael Kriegsmann, Mark Meister, Michael Schneider, Marc A Muley, Thomas Ribeiro, Ricardo |
Keywords: | genetic polymorphisms; lung cancer; renin–angiotensin; hypoxia; angiogenesis | Issue Date: | 18-Dec-2020 | Publisher: | MDPI | Project: | Associação de Estudos Respiratórios and the Portuguese Pulmonology Society | metadata.degois.publication.title: | Cancers | metadata.degois.publication.volume: | 12 | metadata.degois.publication.issue: | 12 | Abstract: | The renin-angiotensin system (RAS) is involved in cell proliferation, immunoinflammatory response, hypoxia and angiogenesis, which are critical biological processes in lung cancer. Our aim was to study the association of putatively functional genetic polymorphisms in genes coding for proteins involved in RAS, hypoxia and angiogenesis with non-small cell lung cancer (NSCLC) prognosis. | URI: | https://hdl.handle.net/10316/105854 | ISSN: | 2072-6694 | DOI: | 10.3390/cancers12123834 | Rights: | openAccess |
| Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
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