Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/10431
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Costa-Balogh, Fátima O. | - |
dc.contributor.author | Åberg, Christoffer | - |
dc.contributor.author | Sousa, João J. S. | - |
dc.contributor.author | Sparr, Emma | - |
dc.date.accessioned | 2009-06-29T14:39:22Z | - |
dc.date.available | 2009-06-29T14:39:22Z | - |
dc.date.issued | 2005-11-08 | - |
dc.identifier.citation | Langmuir. 21:23 (2005) 10307-10310 | en_US |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://hdl.handle.net/10316/10431 | - |
dc.description.abstract | In this paper, we demonstrate, for the first time, how an external osmotic gradient can be used to regulate diffusion of solutes across a lipid membrane. We present experimental and theoretical studies of the transport of different solutes across a monoolein membrane in the presence of an external osmotic gradient. The osmotic gradient introduces phase transformations in the membrane, and it causes nonlinear transport behavior. The external gradient can thus act as a kind of switch for diffusive transport in the skin and in controlled release drug formulations. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | American Chemical Society | en_US |
dc.rights | openAccess | eng |
dc.title | Drug Transport in Responding Lipid Membranes Can Be Regulated by an External Osmotic Gradient | en_US |
dc.type | article | en_US |
dc.identifier.doi | 10.1021/la051947n | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0001-9718-8035 | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Drug Transport in Responding.pdf | 103.94 kB | Adobe PDF | View/Open |
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