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http://hdl.handle.net/10316/103991| Title: | Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis | Authors: | Guerra, Sara Isabel da Silva Mocciaro, Gabriele Gastaldelli, Amalia |
Keywords: | lipidomics; lipotoxicity; mitochondrial dysfunction; non-alcoholic fatty liver disease | Issue Date: | Mar-2022 | Project: | FOIE GRAS project (722619) mtFOIE GRAS project (734719) |
Volume: | 52 | Issue: | 3 | Abstract: | The prevalence of non-alcoholic fatty liver disease (NAFLD) is now 25% in the general population but increases to more than 55% in subjects with obesity and/or type 2 diabetes. Simple steatosis (NAFL) can develop into more severe forms, that is non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma leading to death. | URI: | http://hdl.handle.net/10316/103991 | ISSN: | 0014-2972 1365-2362 |
DOI: | 10.1111/eci.13695 | Rights: | embargoedAccess |
| Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Gastaldelli EJCI 2021 NAFLD-Foie Gras_R1 15set2021 final version with figures.pdf | 713.48 kB | Adobe PDF | View/Open |
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