Please use this identifier to cite or link to this item:
Title: Prescription trends at the end of life in a palliative care unit: observational study
Authors: Peralta, Tatiana
Castel-Branco, Maria Margarida 
Reis-Pina, Paulo
Figueiredo, Isabel Vitória 
Dourado, Marília
Keywords: Drug prescription; Prescription trends; Deprescribing; Palliative care; End of life care; Hospice care
Issue Date: 4-May-2022
Publisher: BMC
Serial title, monograph or event: BMC Palliative Care
Volume: 21
Issue: 1
Abstract: Background: Symptomatic control is essential in palliative care, particularly in end‑of‑life, in which the pathophysiological changes that characterize this last phase of life strengthen the need to carry out an early therapeutic review. Hence, we aim to evaluate the prescribing pattern at a palliative care unit at two different time points: on admission and the day of the patient’s death. Methods: Quantitative, analytic, longitudinal, retrospective and observational study. Participants were adult patients who were admitted and died in a palliative care unit, in Portugal. Sociodemographic, clinical and pharmacological data were collected, including frequencies and routes of administration of schedule prescribed drugs and rescue drugs, from the day of admission until the day of death. Results: 115 patients were included with an average age of 70.0 ± 12.9 years old, 53.9 were male, mostly referred by the Hospital Palliative Care Support Teams. The most common pathology was cancer, mainly in advanced stage. On admission, the median scheduled prescription was seven and “as needed” was three drugs. On the day of death, a decrease of prescriptions was observed. Opioids were always the most prescribed drugs. Near death, there was a higher tendency to prescribe butylscopolamine, midazolam, diazepam and levomepromazine. The most frequent route of drug administration was oral on admission and subcutaneous on the day of death. Conclusions: Polypharmacy is a reality in palliative care despite specialist palliative care teams. A reduction of prescribed drugs was verified, essentially due less comorbidity‑oriented drugs. Further studies are required to analyse the importance of Hospital Palliative Care Support Teams.
ISSN: 1472-684X
DOI: 10.1186/s12904-022-00954-z
Rights: openAccess
Appears in Collections:FFUC- Artigos em Revistas Internacionais
FMUC Medicina - Artigos em Revistas Internacionais
I&D ICBR - Artigos em Revistas Internacionais
I&D CEISUC - Artigos em Revistas Internacionais

Show full item record


checked on Nov 17, 2022


checked on May 2, 2023

Page view(s)

checked on Sep 25, 2023


checked on Sep 25, 2023

Google ScholarTM




This item is licensed under a Creative Commons License Creative Commons