This work received the financial support from the European Union (FEDER funds POCI/01/0145/FEDER/007728 through Programa Operacional Factores de Competitividade— COMPETE) and National Funds (FCT/ MEC, Fundac ~ao para a Ci^encia e Tecnologia and Minist erio da Educac ~ao e Ci^encia) under the Partnership Agreement PT2020 UID/MULTI/04378/2013, and the project (3599-PPCDT) PTDC/DTP-FTO/ 1981/2014 – POCI-01-0145-FEDER-016581. FCT fellowships: SFRH/BD/117931/2016 (M. Espadinha), SFRH/BD/117949/2016 (L. Raimundo), PD/BD/ 114046/2015 (A.S. Gomes), SFRH/BD/96189/2013 (S. Gomes), SFRH/BD/119144/2016 (H. Ramos).

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This work received the financial support from the European Union (FEDER funds POCI/01/0145/FEDER/007728 through Programa Operacional Factores de Competitividade— COMPETE) and National Funds (FCT/ MEC, Fundac ~ao para a Ci^encia e Tecnologia and Minist erio da Educac ~ao e Ci^encia) under the Partnership Agreement PT2020 UID/MULTI/04378/2013, and the project (3599-PPCDT) PTDC/DTP-FTO/ 1981/2014 – POCI-01-0145-FEDER-016581. FCT fellowships: SFRH/BD/117931/2016 (M. Espadinha), SFRH/BD/117949/2016 (L. Raimundo), PD/BD/ 114046/2015 (A.S. Gomes), SFRH/BD/96189/2013 (S. Gomes), SFRH/BD/119144/2016 (H. Ramos).

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1Jun-2017DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer propertiesSoares, Joana; Espadinha, Margarida; Raimundo, Liliana; Ramos, Helena; Gomes, Ana Sara; Gomes, Sara; Loureiro, Joana B.; Inga, Alberto; Reis, Flávio ; Gomes, Célia ; Santos, Maria M. M.; Saraiva, LucíliaarticleopenAccess