PTDC/NAN-MAT/1431/2021

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Primary Data

Project title
PTDC/NAN-MAT/1431/2021
Code
CELLMASKNANO Multifunctional cell membrane-camouflaged polymeric micelles for combination therapy of colorectal cancer
Organization
 

Description

Abstract
Colorectal cancer (CRC) has high prevalence world-wide and increasing mortality observed in Portuguese population [1]. Chemotherapy remains at the forefront of CRC treatment, especially in advanced cases, but has changed little in the past decades. Most of the patients are older than 50 years of age, but the disease is more aggressive in patients that are diagnosed at younger ages. The high drug doses necessary to achieve desired outcomes lead to both acute and long-term side-effects. Considerable number of CRC patients are nonresponsive to the available therapeutics, and the main death cause remains distant metastasis and drug resistance. Therefore, there is an urgent need to develop new, safer and more efficient therapeutics for CRC. Nanomedicine has emerged as a promising approach to improve therapeutic outcomes and reduce side-effects.
 

Publications
(All)

Results 1-4 of 4 (Search time: 0.006 seconds).

Issue DateTitleAuthor(s)TypeAccess
115-Aug-2022New Advances in Biomedical Application of Polymeric MicellesFigueiras, Ana ; Domingues, Cátia ; Jarak, Ivana ; Santos, Ana Isabel ; Parra, Ana ; Pais, Alberto ; Alvarez-Lorenzo, Carmen ; Concheiro, Angel ; Kabanov, Alexander; Cabral, Horacio; Veiga, Francisco articleopenAccess
26-Oct-2023Pediatric Drug Development: Reviewing Challenges and Opportunities by Tracking Innovative TherapiesDomingues, Cátia ; Jarak, Ivana ; Veiga, Francisco ; Dourado, Marília ; Figueiras, Ana articleopenAccess
321-Feb-2023The Debate between the Human Microbiota and Immune System in Treating Aerodigestive and Digestive Tract Cancers: A ReviewDomingues, Cátia ; Cabral, Cristiana Isabel Lima ; Jarak, Ivana ; Veiga, Francisco ; Dourado, Marília ; Figueiras, Ana articleopenAccess
43-Feb-2023The Role of Cyclodextrins in COVID-19 Therapy-A Literature ReviewAlmeida, Beatriz C. ; Domingues, Cátia ; Mascarenhas-Melo, Filipa ; Silva, Inês; Jarak, Ivana ; Veiga, Francisco ; Figueiras, Ana articleopenAccess