This work was funded by fellowship SFRH/BD/51576/2011 and grants UID/NEU/04539 COMPETE (POCI-01-0145-FEDER-007440), PEst-OE/QUI/UI0612/2013, and FCOMP-01-0124- FEDER-020978 financed by FEDER through the “Programa Operacional Factores de Competitividade, COMPETE” and by national funds through “FCT, Fundação para a Ciência e a Tecnologia” (project PTDC/QUI-BIQ/119657/2010).

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This work was funded by fellowship SFRH/BD/51576/2011 and grants UID/NEU/04539 COMPETE (POCI-01-0145-FEDER-007440), PEst-OE/QUI/UI0612/2013, and FCOMP-01-0124- FEDER-020978 financed by FEDER through the “Programa Operacional Factores de Competitividade, COMPETE” and by national funds through “FCT, Fundação para a Ciência e a Tecnologia” (project PTDC/QUI-BIQ/119657/2010).