Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/88878
DC FieldValueLanguage
dc.contributor.authorFerreira, Brígida da Costa-
dc.contributor.authorMavroidis, Panayiotis-
dc.contributor.authorDias, Joana-
dc.contributor.authorRocha, Humberto-
dc.date.accessioned2020-02-18T09:31:27Z-
dc.date.available2020-02-18T09:31:27Z-
dc.date.issued2019-
dc.identifier.isbn978-981-10-9022-6pt
dc.identifier.urihttps://hdl.handle.net/10316/88878-
dc.description.abstractIn intensity modulated radiation therapy (IMRT), the dose in each voxel of the organs at risk (OAR) can be strongly reduced compared to conformal radiation therapy (RT). Due to the sensitivity of late side-effects to fraction size, a smaller dose per fraction in the normal tissues represent an increased tolerance to RT. This expected reduction in biological effect may then be used as an additional degree of freedom during IMRT optimization. In this study, the comparison between plans optimized with and without a voxel-based fractionation correction was made.pt
dc.language.isoengpt
dc.publisherSpringerpt
dc.rightsopenAccesspt
dc.subjectRadiation therapypt
dc.subjectIMRT optimizationpt
dc.titleIncorporating the Local Biological Effect of Dose Per Fraction in IMRT Inverse Optimizationpt
dc.typebookPart-
degois.publication.firstPage413pt
degois.publication.lastPage416pt
degois.publication.titleIFMBEpt
dc.relation.publisherversionhttps://link.springer.com/chapter/10.1007/978-981-10-9023-3_74#citeaspt
dc.peerreviewedyespt
dc.identifier.doi10.1007/978-981-10-9023-3_74pt
degois.publication.volume68pt
dc.date.embargo2019-01-01*
uc.date.periodoEmbargo0pt
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypebookPart-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.languageiso639-1en-
crisitem.author.researchunitINESC Coimbra – Institute for Systems Engineering and Computers at Coimbra-
crisitem.author.researchunitCeBER – Centre for Business and Economics Research-
crisitem.author.orcid0000-0002-5981-4469-
Appears in Collections:I&D CeBER - Livros e Capítulos de Livros
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