Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/7904
Title: Regulation of AMPA Receptor Activity, Synaptic Targeting and Recycling: Role in Synaptic Plasticity
Authors: Gomes, André R. 
Correia, Susana S. 
Carvalho, Ana Luísa 
Duarte, Carlos B. 
Issue Date: 2003
Citation: Neurochemical Research. 28:10 (2003) 1459-1473
Abstract: The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors for the neurotransmitter glutamate are oligomeric structures responsible for most fast excitatory responses in the central nervous system. The activity of AMPA receptors can be directly regulated by protein phosphorylation, which may also affect the interaction with intracellular proteins and, consequently, their recycling and localization to defined postsynaptic sites. This review focuses on recent advances in understanding the dynamic regulation of AMPA receptors, on a short- and long-term basis, and its implications in synaptic plasticity.
URI: http://hdl.handle.net/10316/7904
DOI: 10.1023/A:1025610122776
Rights: openAccess
Appears in Collections:FCTUC Ciências da Vida - Artigos em Revistas Internacionais

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