Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/5791
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dc.contributor.authorMadureira, Maria do Céu de-
dc.contributor.authorMartins, Ana Paula-
dc.contributor.authorGomes, Milene-
dc.contributor.authorPaiva, Jorge-
dc.contributor.authorCunha, António Proença da-
dc.contributor.authorRosário, Virgílio do-
dc.date.accessioned2008-09-26T17:41:49Z-
dc.date.available2008-09-26T17:41:49Z-
dc.date.issued2002en_US
dc.identifier.citationJournal of Ethnopharmacology. 81:1 (2002) 23-29en_US
dc.identifier.urihttp://hdl.handle.net/10316/5791-
dc.description.abstractThe present study investigates the antimalarial activity of 13 medicinal plants used in traditional medicine in S. Tomé and Prí­ncipe (STP) islands in the Gulf of Guinea, aiming at identifying the most effective plants for further research. Fieldwork was carried out with the collaboration of 37 traditional healers from both islands, during an ethnobotanical study, which was conducted from 1993 to 1999. Our results indicate that the traditional healers in STP use several medicinal plants against fever and/or [`]malaria' which reveal strong antiparasitic activity in vitro: four of the plant extracts have evident antiplasmodial activity against chloroquine resistant Plasmodium falciparum, with IC50 values <10 [mu]g/ml, and also revealed hepatic schizontocidal activity (<5-35 [mu]g/ml). In vivo, the extracts caused partial reduction of Plasmodium berghei parasitaemia in mice.en_US
dc.description.urihttp://www.sciencedirect.com/science/article/B6T8D-452WHB8-3/1/6a9a0385ccbedbaacf74ee6a1ac95219en_US
dc.format.mimetypeaplication/PDFen
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectAntimalarial activityen_US
dc.subjectMedicinal plantsen_US
dc.subjectStruchium sparganophorumen_US
dc.subjectTithonia diversifoliaen_US
dc.subjectPycnanthus angolensisen_US
dc.subjectMorinda lucidaen_US
dc.titleAntimalarial activity of medicinal plants used in traditional medicine in S. Tomé and Prí­ncipe islandsen_US
dc.typearticleen_US
dc.identifier.doi10.1016/S0378-8741(02)00005-3-
item.fulltextCom Texto completo-
item.grantfulltextopen-
item.languageiso639-1en-
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