Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/45374
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pontrelli, Giuseppe | - |
dc.contributor.author | Lauricella, Marco | - |
dc.contributor.author | Ferreira, José Augusto | - |
dc.contributor.author | Pena, Gonçalo | - |
dc.date.accessioned | 2017-12-21T14:56:23Z | - |
dc.date.issued | 2017 | - |
dc.identifier.uri | https://hdl.handle.net/10316/45374 | - |
dc.description.abstract | We present a multi-layer mathematical model to describe the the transdermal drug release from an iontophoretic system. The Nernst-Planck equation describe the basic convection-diffusion process, with the electric potential obtained by Laplace equation. These equations are complemented with suitable interface and boundary conditions in a multi-domain. The stability of the mathematical problem is discussed in different scenarios and a finite-difference method is used to solve the coupled system. Numerical experiments are included to illustrate the drug dynamics under different conditions. | por |
dc.language.iso | por | por |
dc.publisher | Oxford University Press | por |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147205/PT | por |
dc.rights | embargoedAccess | - |
dc.title | Iontophoretic transdermal drug delivery: a multi-layered approach | por |
dc.type | article | - |
degois.publication.firstPage | 559 | por |
degois.publication.lastPage | 576 | por |
degois.publication.issue | 4 | por |
degois.publication.title | Mathematical Medicine and Biology | por |
dc.relation.publisherversion | https://doi.org/10.1093/imammb/dqw017 | por |
dc.peerreviewed | yes | por |
dc.identifier.doi | 10.1093/imammb/dqw017 | - |
degois.publication.volume | 34 | por |
dc.date.embargo | 2018-12-21T14:56:23Z | - |
uc.controloAutoridade | Sim | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | pt | - |
crisitem.author.dept | Faculty of Sciences and Technology | - |
crisitem.author.dept | Faculty of Sciences and Technology | - |
crisitem.author.parentdept | University of Coimbra | - |
crisitem.author.parentdept | University of Coimbra | - |
crisitem.author.researchunit | CMUC - Centre for Mathematics of the University of Coimbra | - |
crisitem.author.researchunit | CMUC - Centre for Mathematics of the University of Coimbra | - |
crisitem.author.orcid | 0000-0002-5226-2905 | - |
crisitem.author.orcid | 0000-0003-0552-8069 | - |
Appears in Collections: | I&D CMUC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
paper3.pdf | 4.54 MB | Adobe PDF | View/Open |
SCOPUSTM
Citations
7
checked on Apr 15, 2024
WEB OF SCIENCETM
Citations
5
checked on Mar 2, 2024
Page view(s) 20
798
checked on Apr 16, 2024
Download(s)
193
checked on Apr 16, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.