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https://hdl.handle.net/10316/44680| Title: | The effect of reversible binding sites on drug release from drug eluting stents | Authors: | Ferreira, José Augusto Naghipoor, Jahed Oliveira, Paula de |
Issue Date: | 2014 | Publisher: | J. Vigo - Aguiar | Project: | info:eu-repo/grantAgreement/FCT/COMPETE/132981/PT | Serial title, monograph or event: | Proceedings of the 14th International Conference on Computational and Mathematical Methods in Science and Engineering | Volume: | II | Place of publication or event: | Costa Ballena, Rota, Cádiz (Spain) | Abstract: | A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug eluting stent is proposed. The reversible reaction between the drug and the arterial tissue binding sites are taken into account. The proposed model accounts for the different nature of the therapeutic compounds used. The numerical results are obtained using an IMEX finite element method in the variational form. | URI: | https://hdl.handle.net/10316/44680 | Rights: | openAccess |
| Appears in Collections: | I&D CMUC - Artigos e Resumos em Livros de Actas |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| JAF_JN_PO.pdf | 453.56 kB | Adobe PDF | View/Open |
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