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https://hdl.handle.net/10316/110984
Título: | Bioengineered materials with selective antimicrobial toxicity in biomedicine | Autor: | Makvandi, Pooyan Song, Hao Yiu, Cynthia K Y Sartorius, Rossella Zare, Ehsan Nazarzadeh Rabiee, Navid Wu, Wei-Xi Paiva-Santos, Ana Cláudia Wang, Xiang-Dong Yu, Cheng-Zhong Tay, Franklin R |
Palavras-chave: | Antimicrobial nanotechnology; Immumodualtion; Selective toxicity; Smart nanomaterials; Targeting microorganism | Data: | 24-Fev-2023 | Editora: | Springer Nature | Título da revista, periódico, livro ou evento: | Military Medical Research | Volume: | 10 | Número: | 1 | Resumo: | Fungi and bacteria afflict humans with innumerous pathogen-related infections and ailments. Most of the commonly employed microbicidal agents target commensal and pathogenic microorganisms without discrimination. To distinguish and fight the pathogenic species out of the microflora, novel antimicrobials have been developed that selectively target specific bacteria and fungi. The cell wall features and antimicrobial mechanisms that these microorganisms involved in are highlighted in the present review. This is followed by reviewing the design of antimicrobials that selectively combat a specific community of microbes including Gram-positive and Gram-negative bacterial strains as well as fungi. Finally, recent advances in the antimicrobial immunomodulation strategy that enables treating microorganism infections with high specificity are reviewed. These basic tenets will enable the avid reader to design novel approaches and compounds for antibacterial and antifungal applications. | URI: | https://hdl.handle.net/10316/110984 | ISSN: | 2054-9369 | DOI: | 10.1186/s40779-023-00443-1 | Direitos: | openAccess |
Aparece nas coleções: | FFUC- Artigos em Revistas Internacionais |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Bioengineered-materials-with-selective-antimicrobial-toxicity-in-biomedicineMilitary-Medical-Research.pdf | 2.88 MB | Adobe PDF | Ver/Abrir |
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