Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105267
DC Field | Value | Language |
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dc.contributor.author | Sousa, Raquel | - |
dc.contributor.author | Figueirinha, Artur | - |
dc.contributor.author | Batista, Maria Teresa | - |
dc.contributor.author | Pina, Maria Eugénia | - |
dc.date.accessioned | 2023-02-13T12:25:33Z | - |
dc.date.available | 2023-02-13T12:25:33Z | - |
dc.date.issued | 2021-07-27 | - |
dc.identifier.issn | 1420-3049 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105267 | - |
dc.description.abstract | Cymbopogon citratus DC (Stapf.) is a perennial grass and it is distributed around the world. It is used as a condiment for food and beverage flavouring in the form of infusions and decoctions of its dried leaves. Our previous studies have shown antioxidant, anti-inflammatory and gastroprotective activities for the infusion and its phenolic fractions. The aim of the present work was to develop oral dosage forms from a Cymbopogon citratus extract to be used as a functional food with antioxidant properties. Initially, an essential oil-free infusion was prepared, lyophilized and characterized by HPLC-PDA. Total phenols were quantified with the Folin-Ciocalteu method and the antioxidant activity was assessed by DPPH assay. Gelatine capsules containing the extract with different excipients, selected after DSC and IR trials, were prepared. A formulation exhibiting better antioxidant behaviour in a gastric environment was attained. These results suggest that the proposed formulation for this extract could be a valuable antioxidant product and, consequently, make an important contribution to "preventing" and minimizing diseases related to oxidative stress conditions. | pt |
dc.language.iso | eng | pt |
dc.publisher | MDPI | pt |
dc.relation | POCI/01/ 0145/FEDER/007265 | pt |
dc.relation | UID/QUI/50006/2013 | pt |
dc.relation | Programa de Cooperación Interreg V-A España–Portugal (POCTEP) 2014–2020 (project 0377_IBERPHENOL_6_E) | pt |
dc.relation | UIDB/00102/2020 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | Cymbopogon citratus | pt |
dc.subject | gelatine capsules | pt |
dc.subject | biological activity | pt |
dc.subject | chemical stability | pt |
dc.subject.mesh | Administration, Oral | pt |
dc.subject.mesh | Antioxidants | pt |
dc.subject.mesh | Capsules | pt |
dc.subject.mesh | Chromatography, High Pressure Liquid | pt |
dc.subject.mesh | Cymbopogon | pt |
dc.subject.mesh | Drug Compounding | pt |
dc.subject.mesh | Excipients | pt |
dc.subject.mesh | Flavonoids | pt |
dc.subject.mesh | Gelatin | pt |
dc.subject.mesh | Plant Extracts | pt |
dc.subject.mesh | Plant Leaves | pt |
dc.subject.mesh | Polyphenols | pt |
dc.subject.mesh | Tannins | pt |
dc.title | Formulation Effects in the Antioxidant Activity of Extract from the Leaves of Cymbopogon citratus (DC) Stapf | pt |
dc.type | article | - |
degois.publication.firstPage | 4518 | pt |
degois.publication.issue | 15 | pt |
degois.publication.title | Molecules | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/molecules26154518 | pt |
degois.publication.volume | 26 | pt |
dc.date.embargo | 2021-07-27 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.project.grantno | CIEPQPF- Chemical Engineering and Renewable Resources for Sustainability | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CIEPQPF – Chemical Process Engineering and Forest Products Research Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0003-3064-5718 | - |
crisitem.author.orcid | 0000-0003-4183-6202 | - |
crisitem.author.orcid | 0000-0003-0189-1370 | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais I&D CERES - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Formulation-effects-in-the-antioxidant-activity-of-extract-from-the-leaves-of-cymbopogon-citratus-Dc-stapfMolecules.pdf | 1.71 MB | Adobe PDF | View/Open |
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