Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/103309
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Caçador, Catarina | - |
dc.contributor.author | Teixeira-Lemos, Edite | - |
dc.contributor.author | Oliveira, Jorge | - |
dc.contributor.author | Pinheiro, João | - |
dc.contributor.author | Teixeira-Lemos, Luís | - |
dc.contributor.author | Ramos, Fernando | - |
dc.date.accessioned | 2022-11-04T09:23:34Z | - |
dc.date.available | 2022-11-04T09:23:34Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1660-4601 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/103309 | - |
dc.description.abstract | The aim of this study was to evaluate the prevalence of polypharmacy and potentially inappropriate medications (PIMs) in a population of older adults living in nursing homes. Furthermore, we also intended to assess the possible association between polypharmacy, potentially inappropriate medications and cognitive impairment in institutionalized older adults. A cross-sectional study analyzed data from 193 nursing home residents in the district of Viseu, Portugal, between September 2018 and June 2019, with a mean age of 82.4 ± 6.2 years (ranging from 65 to 95 years old); 72.5% (n = 140) were female participants. Major polypharmacy was presented in 80.8% of the study population, who took 7.6 ± 3.3 drugs per day. Using the Beers Criteria, we found that 79.3% took PIMs. There was a positive association between polypharmacy and PIM (p < 0.001), showing that higher medicines intake increased the number of PIMs. Polypharmacy was not associated with the functionality of the older adults to perform activities of daily living, but was associated with cognitive impairment. The older adults with lower scores on the Mini Mental State Examination (MMSE) took more drugs (p = 0.039) and used more PIM (p < 0.001). Moreover, patients taking five or more prescription drugs per day (major polypharmacy) consuming any psychiatric, gastrointestinal or oral antidiabetic agents (regardless of whether they were considered potentially inappropriate or not) had higher odds of displaying cognitive impairment than those who did not (p < 0.05). Older adult residents of the studied nursing homes were potentially affected by polypharmacy and inappropriate polypharmacy. This observation reveals the need to adopt and implement strategies that make drug therapy more adequate and safer for older adults. | pt |
dc.language.iso | eng | pt |
dc.relation | FCT - UIDB/50006/2 20 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject | nursing homes | pt |
dc.subject | polypharmacy | pt |
dc.subject | potentially inappropriate medications | pt |
dc.subject | cognitive assessment | pt |
dc.subject.mesh | Activities of Daily Living | pt |
dc.subject.mesh | Aged | pt |
dc.subject.mesh | Aged, 80 and over | pt |
dc.subject.mesh | Cognition | pt |
dc.subject.mesh | Cross-Sectional Studies | pt |
dc.subject.mesh | Female | pt |
dc.subject.mesh | Humans | pt |
dc.subject.mesh | Inappropriate Prescribing | pt |
dc.subject.mesh | Portugal | pt |
dc.subject.mesh | Prevalence | pt |
dc.subject.mesh | Polypharmacy | pt |
dc.subject.mesh | Potentially Inappropriate Medication List | pt |
dc.title | The Prevalence of Polypharmacy and Potentially Inappropriate Medications and Its Relationship with Cognitive Status in Portuguese Institutionalized Older Adults: A Cross-Sectional Study | pt |
dc.type | article | - |
degois.publication.firstPage | 2637 | pt |
degois.publication.issue | 5 | pt |
degois.publication.title | International Journal of Environmental Research and Public Health | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.3390/ijerph19052637 | pt |
degois.publication.volume | 19 | pt |
dc.date.embargo | 2022-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
crisitem.author.researchunit | ICBR Coimbra Institute for Clinical and Biomedical Research | - |
crisitem.author.researchunit | CIDAF - Research Unit for Sport and Physical Activity | - |
crisitem.author.parentresearchunit | Faculty of Medicine | - |
crisitem.author.orcid | 0000-0002-0673-8060 | - |
crisitem.author.orcid | 0000-0002-6346-8319 | - |
crisitem.author.orcid | 0000-0001-8666-1819 | - |
crisitem.author.orcid | 0000-0002-6043-819X | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
SCOPUSTM
Citations
9
checked on Mar 25, 2024
WEB OF SCIENCETM
Citations
8
checked on Mar 2, 2024
Page view(s)
68
checked on Mar 26, 2024
Download(s)
92
checked on Mar 26, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License