Cavadas, Cláudia
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Credit Name
Cavadas, Cláudia
Name
Cavadas, Cláudia
Variants
Cavadas, Cláudia Margarida Gonçalves
Unidade de I&D
Personal Site
Email
ccavadas@uc.pt
Other emails
Scopus Author ID
Researcher ID
Status
UC Researcher
Biography
My academic journey began with a Pharmaceutical Sciences Degree (PharmD, 1991) and a Master's degree in Cell Biology (1995), Univ. Coimbra. I completed my doctoral studies in Pharmacology in 2002 at the same institution, with my PhD thesis work conducted at the Division of Hypertension, CHUV-UNIL, Lausanne, Switzerland (1998 -2001), supported by a competitive national fellowship from the Portuguese Foundation for Science and Technology (FCT). In 2017, I achieved my Habilitation in Pharmacology, Faculty of Pharmacy of the Univ. of Coimbra (FFUC).
Currently, I am Associate Professor at the Dep.of Pharmacology, Faculty of Pharmacy, Univ. Coimbra; Since 2008, I launched and coordinate the "Neuroendocrinology and Aging Group" at CNC/CIBB, Univ. Coimbra, that is contributing significantly to produce new knowledge in aging and age-related diseases research. I also hold influential positions in various organizations, including membership on the Scientific Council Health and Life Sciences of the Portuguese Foundation for Science and Technology and representation for Portugal in the European Research Area Forum, European Excellence Initiative. Additionally, I sit on the Board of Directors of the collaborative laboratory AccelBio, that foster Translation and Drug Discovery.
My career is also characterized by leadership positions. As Vice-rector for Research (Univ. of Coimbra; 2019-2023), I shaped the university's research strategy. As elected Vice President of the European network of 40 universities, CoimbraGroup, I promoted international collaboration. Additionally, as Director & President of the Scientific Council of the Institute for Interdisciplinary Research, Univ. of Coimbra, I promoted interdisciplinary research and innovation. I was elected President in the Portuguese Society of Pharmacology, coordinator of the Depart. Pharmacology (FFUC). Furthermore, I coordinated the Science Communication Office at CNC-UC.
Currently, I am Associate Professor at the Dep.of Pharmacology, Faculty of Pharmacy, Univ. Coimbra; Since 2008, I launched and coordinate the "Neuroendocrinology and Aging Group" at CNC/CIBB, Univ. Coimbra, that is contributing significantly to produce new knowledge in aging and age-related diseases research. I also hold influential positions in various organizations, including membership on the Scientific Council Health and Life Sciences of the Portuguese Foundation for Science and Technology and representation for Portugal in the European Research Area Forum, European Excellence Initiative. Additionally, I sit on the Board of Directors of the collaborative laboratory AccelBio, that foster Translation and Drug Discovery.
My career is also characterized by leadership positions. As Vice-rector for Research (Univ. of Coimbra; 2019-2023), I shaped the university's research strategy. As elected Vice President of the European network of 40 universities, CoimbraGroup, I promoted international collaboration. Additionally, as Director & President of the Scientific Council of the Institute for Interdisciplinary Research, Univ. of Coimbra, I promoted interdisciplinary research and innovation. I was elected President in the Portuguese Society of Pharmacology, coordinator of the Depart. Pharmacology (FFUC). Furthermore, I coordinated the Science Communication Office at CNC-UC.
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Results 1-34 of 34 (Search time: 0.123 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2015 | Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In Vitro | Martins, João ; Elvas, Filipe ; Brudzewsky, Dan; Martins, Tânia ; Kolomiets, Bogdan; Tralhão, Pedro ; Gøtzsche, Casper R.; Cavadas, Cláudia ; Castelo-Branco, Miguel ; Woldbye, David P. D. ; Picaud, Serge; Santiago, Ana R. | article | openAccess |
| 2 | 25-Jul-2014 | Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress | Faria, R. ; Santana, M. M. ; Aveleira, C. A. ; Simões, C. ; Maciel, E. ; Melo, T. ; Santinha, D. ; Oliveira, M. M. ; Peixoto, F. ; Domingues, P. ; Cavadas, C. ; Domingues, M. R. M. | article | openAccess |
| 3 | 2003 | Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adrenal chromaffin cells through the AT1 receptor | Cavadas, Cláudia ; Grand, Daniela ; Mosimann, François ; Cotrim, Maria Dulce ; Ribeiro, Carlos Alberto Fontes ; Brunner, Hans R. ; Grouzmann, Eric | article | openAccess |
| 4 | 14-Nov-2020 | Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats | Nunes, Sara ; Viana, Sofia D. ; Preguiça, Inês ; Alves, André ; Fernandes, Rosa ; Teodoro, João S. ; Figueirinha, Artur ; Salgueiro, Lígia ; Silva, Sara; Jarak, Ivana ; Carvalho, Rui A. ; Cavadas, Cláudia ; Rolo, Anabela P. ; Palmeira, Carlos M. ; Pintado, Maria M.; Reis, Flávio | article | openAccess |
| 5 | 23-Nov-2021 | Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics | Nunes, Sara ; Viana, Sofia D. ; Preguiça, Inês ; Alves, André ; Fernandes, Rosa ; Teodoro, João S. ; Matos, Patrícia ; Figueirinha, Artur ; Salgueiro, Lígia ; André, Alexandra; Silva, Sara; Jarak, Ivana ; Carvalho, Rui A. ; Cavadas, Cláudia ; Rolo, Anabela P. ; Palmeira, Carlos M. ; Pintado, Maria M.; Reis, Flávio | article | openAccess |
| 6 | 11-May-2016 | Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway | Cunha-Santos, Janete ; Duarte-Neves, Joana ; Carmona, Vitor ; Guarente, Leonard; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 7 | 2016 | Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation | Ferreira-Marques, Marisa; Aveleira, Célia A. ; Carmo-Silva, Sara; Botelho, Mariana ; Pereira de Almeida, Luís ; Cavadas, Cláudia | article | openAccess |
| 8 | 5-Jul-2006 | Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion | Cavadas, Cláudia ; Céfai, Daniel ; Rosmaninho-Salgado, Joana ; Vieira-Coelho, Maria Augusta ; Moura, Eduardo ; Busso, Nathalie ; Pedrazzini, Thierry ; Grand, Daniela ; Rotman, Samuel ; Waeber, Bernard ; Aubert, Jean-François ; Grouzmann, Eric | article | openAccess |
| 9 | 5-Nov-2019 | Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases | Gomes, Pedro ; Leal, Helena; Mendes, Alexandrina F. ; Reis, Flávio ; Cavadas, Cláudia | article | embargoedAccess |
| 10 | Mar-2018 | Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice | Marques, Ana Patrícia; Cunha-Santos, Janete; Leal, Helena; Sousa-Ferreira, Lígia ; Pereira de Almeida, Luís ; Cavadas, Cláudia ; Rosmaninho-Salgado, Joana | article | openAccess |
| 11 | 2013 | Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system | Vindeirinho, Joana ; Costa, Gabriel N. ; Correia, Mariana B. ; Cavadas, Cláudia ; Santos, Paulo | article | openAccess |
| 12 | 2011 | Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat | Martins, João ; Castelo-Branco, Miguel ; Batista, Ana ; Oliveiros, Bárbara ; Santiago, Ana Raquel ; Galvão, Joana ; Fernandes, Eduarda; Carvalho, Félix ; Cavadas, Cláudia ; Ambrósio, A. Francisco | article | openAccess |
| 13 | Jan-2014 | Emerging novel roles of neuropeptide Y in the retina: from neuromodulation to neuroprotection | Santos-Carvalho, Ana ; Álvaro, Ana Rita ; Martins, João ; Ambrósio, António Francisco ; Cavadas, Cláudia | article | openAccess |
| 14 | 2018 | Expression and function of neuropeptide y receptors in human articular cartilage: influence of gender and osteoarthritis | Ferreira, Inês Sofia dos Santos Rodrigues ; Sousa, Cátia Moreira ; Silva, Soraia; Judas, Fernando João Monteiro ; Cavadas, Cláudia Margarida Gonçalves ; Mendes, Alexandrina Ferreira | article | openAccess |
| 15 | 5-Mar-2014 | Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro | Sousa-Ferreira, Lígia ; Aveleira, Célia ; Botelho, Mariana ; Álvaro, Ana Rita ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 16 | Dec-2023 | Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome | Ferreira-Marques, Marisa ; Carvalho, André; Franco, Ana Catarina ; Leal, Ana; Botelho, Mariana ; Carmo-Silva, Sara ; Águas, Rodolfo ; Cortes, Luísa ; Lucas, Vasco; Real, Ana Carolina; López-Otín, Carlos; Nissan, Xavier; Almeida, Luís Pereira de ; Cavadas, Cláudia ; Aveleira, Célia A. | article | openAccess |
| 17 | 2007 | Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells | Rosmaninho-Salgado, Joana ; Araújo, Inês M. ; Álvaro, Ana Rita ; Duarte, Emília P. ; Cavadas, Cláudia | article | openAccess |
| 18 | Nov-2012 | Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla | Santana, Magda M. ; Chung, Kuei-Fang; Vukicevic, Vladimir; Salgado, Joana Rosmaninho ; Kanczkowski, Waldemar; Cortez, Vera; Hackmann, Klaus; Bastos, Carlos A.; Mota, Alfredo ; Schrock, Evelin; Bornstein, Stefan R.; Cavadas, Cláudia ; Ehrhart-Bornstein, Monika | article | openAccess |
| 19 | Mar-2021 | Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea | Gaspar, Laetitia S. ; Hesse, Janina; Yalçin, Müge; Santos, Bárbara; Carvalhas-Almeida, Catarina; Ferreira, Mafalda ; Moita, Joaquim; Relógio, Angela; Cavadas, Cláudia ; Álvaro, Ana Rita | article | openAccess |
| 20 | 2011 | Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats | Sousa-Ferreira, Lígia ; Garrido, Manuel Joaquim Marques ; Nascimento-Ferreira, Isabel ; Nóbrega, Clévio ; Carvalho, Ana dos Santos ; Álvaro, Ana Rita Costa Silva ; Salgado, Joana Rosmaninho ; Kaster, Manuella; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 21 | 8-Feb-2021 | Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease | Duarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de | article | openAccess |
| 22 | 2008 | Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy | Álvaro, A. R. ; Martins, J. ; Costa, A. C. ; Fernandes, E. ; Carvalho, F. ; Ambrósio, A. F. ; Cavadas, C. | article | openAccess |
| 23 | 16-May-2013 | Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate | Santos-Carvalho, A. ; Elvas, F. ; Álvaro, A. R. ; Ambrósio, A. F. ; Cavadas, C. | article | openAccess |
| 24 | 2007 | NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells | Álvaro, Ana Rita ; Rosmaninho-Salgado, Joana ; Santiago, Ana Raquel ; Martins, João ; Aveleira, Célia ; Santos, Paulo F. ; Pereira, Tiago ; Gouveia, Denisa ; Carvalho, Ana Luísa ; Grouzmann, Eric ; Ambrósio, António Francisco ; Cavadas, Cláudia | article | openAccess |
| 25 | Dec-2001 | NPY regulates catecholamine secretion from human adrenal chromaffin cells | Cavadas, Cláudia ; Silva, António P. ; Mosimann, François ; Cotrim, Maria Dulce ; Ribeiro, Carlos Alberto Fontes ; Brunner, Hans R. ; Grouzmann, Eric | article | openAccess |
| 26 | 2007 | NPY Y1 receptor is not involved in the hemodynamic response to an acute cold pressor test in mice | Cavadas, Cláudia ; Waeber, Bernard ; Pedrazzini, Thierry ; Grand, Daniela ; Aubert, Jean-François ; Buclin, Thierry ; Grouzmann, Eric | article | openAccess |
| 27 | 2005 | Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedative activity in mice | Cotrim, M. D. ; Figueiredo, I. V. ; Cavadas, C. ; Cunha, A. Proença da ; Caramona, M. M. ; Macedo, T. R. A. | article | openAccess |
| 28 | 2021 | PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons | Ferreira-Marques, Marisa ; Carvalho, André ; Cavadas, Cláudia ; Aveleira, Célia A. | article | openAccess |
| 29 | Dec-2013 | Progenitor cells in chromospheres: in response to Arthur S. Tischler | Santana, Magda M. ; Ehrhart-Bornstein, Monika; Cavadas, Cláudia | article | openAccess |
| 30 | 11-May-2011 | Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons | Sousa-Ferreira, Lígia ; Álvaro, Ana Rita ; Aveleira, Célia ; Santana, Magda ; Brandão, Inês ; Kügler, Sebastian ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
| 31 | Feb-2022 | Skin senescence: mechanisms and impact on whole-body aging | Franco, Ana Catarina ; Aveleira, Célia A. ; Cavadas, Cláudia | article | embargoedAccess |
| 32 | Feb-2023 | The impact of insomnia on frailty and the hallmarks of aging | Carvalhas-Almeida, Catarina ; Cavadas, Cláudia ; Álvaro, Ana Rita | article | openAccess |
| 33 | 9-Apr-2020 | Trehalose alleviates the phenotype of Machado-Joseph disease mouse models | Santana, Magda M. ; Paixão, Susana ; Cunha-Santos, Janete; Silva, Teresa Pereira ; Trevino-Garcia, Allyson; Gaspar, Laetitia da Silva ; Nóbrega, Clévio ; Nobre, Rui J. ; Cavadas, Cláudia ; Greif, Hagar; Almeida, Luís Pereira de | article | openAccess |
| 34 | 2005 | Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats | Silva, Ana P. ; Xapelli, Sara ; Pinheiro, Paulo S. ; Ferreira, Raquel ; Lourenço, Joana ; Cristóvão, Armando ; Grouzmann, Eric ; Cavadas, Cláudia ; Oliveira, Catarina R. ; Malva, João O. | article | openAccess |