Laranjinha, João

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Credit Name
Laranjinha, João
 
Name
Laranjinha, João
 
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Laranjinha, João
 
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Status
UC Researcher
Biography
João Laranjinha is professor of Biochemistry and Molecular Biology at the Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal. He graduated in Pharmaceutical Sciences (University of Coimbra) in 1984 and got a PhD in Biochemistry (University of Coimbra) in 1996. He did Postdoc studies with Enrique Cadenas in 1997-1998 at the Dept. Molecular Pharmacology and Toxicology, University Southern California, Los Angeles, USA. His research is focused on the functional impact of nitric oxide in the brain as a neurometabolic regulator and as a mediator of neurovascular coupling with impact in aging and neurodegeneration. He is also interested in dietary nitrite-driven regulatory processes, encompassing the non-enzymatic production of nitric oxide along the nitrate:nitrite:NO pathway. He has been awarded several prizes, including the Science and Humanity award by The Oxygen Club of California and is member of the editorial board of major journals in his area of research, including Redox Biology, Free Radical Biology and Medicine, Archives of Biochemistry and Biophysics, Free Radical Research and Biofactors. He has chaired the organizing and scientific committees of several international conferences, including the European (SFRRE 2007) and International (SFRRI 2018) meetings of the Society for Free Radical Research. He has been member of the council of the European Society for Neurochemistry and the European Society for Free Radical Research for several years and President of the Portuguese Biochemical Society (2014-18). Currently, he serves as member of the Advanced Courses Committee of FEBS and as the president of the General Assembly of the Portuguese Biochemical Society.
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Publications

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Date Issued:  [2010 TO 2020]

Results 1-35 of 35 (Search time: 0.302 seconds).

Issue DateTitleAuthor(s)TypeAccess
1Sep-2015Ação de flavonoides na doença inflamatória intestinalJin, LuyiotheropenAccess
22018Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the HippocampusLourenço, Cátia F. ; Ledo, Ana ; Caetano, Miguel ; Barbosa, Rui M. ; Laranjinha, João articleopenAccess
3Jun-2014Alzheimer: diabetes tipo 3?Almeida, Mariana Matos deotheropenAccess
45-Dec-2012Biological role of nitrite and nitric oxide in the stomach: from diet to protein tyrosine with implications for gastric physiologyRocha, Bárbara Silva doctoralThesisopenAccess
515-Jun-2013Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brainSantos, Ricardo M. ; Rodrigues, Marcelo S. ; Laranjinha, João ; Barbosa, Rui M. articleopenAccess
6Jul-2014Diabetes tipo 3: uma nova perspectiva sobre a doença de AlzheimerMarques, João Gabriel de OliveiraotheropenAccess
7Sep-2015Doença de Alzheimer e resistência à insulinaTuca, OctavianotheropenAccess
8Oct-2017European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G.; Lopez, Manuela G.; Olaso-Gonzalez, Gloria; Petry, Andreas; Schulz, Rainer; Vina, Jose; Winyard, Paul; Abbas, Kahina; Ademowo, Opeyemi S.; Afonso, Catarina B.; Andreadou, Ioanna; Antelmann, Haike; Antunes, Fernando; Aslan, Mutay; Bachschmid, Markus M.; Barbosa, Rui M. ; Belousov, Vsevolod; Berndt, Carsten; Bernlohr, David; Bertrán, Esther; Bindoli, Alberto; Bottari, Serge P.; Brito, Paula M. ; Carrara, Guia; Casas, Ana I.; Chatzi, Afroditi; Chondrogianni, Niki; Conrad, Marcus; Cooke, Marcus S.; Costa, João G.; Cuadrado, Antonio; My-Chan Dang, Pham; De Smet, Barbara; Debelec-Butuner, Bilge; Dias, Irundika H K; Dunn, Joe Dan; Edson, Amanda J; El Assar, Mariam; El-Benna, Jamel; Ferdinandy, Péter; Fernandes, Ana S.; Fladmark, Kari E.; Förstermann, Ulrich; Giniatullin, Rashid; Giricz, Zoltán; Görbe, Anikó; Griffiths, Helen; Hampl, Vaclav; Hanf, Alina; Herget, Jan; Hernansanz-Agustín, Pablo; Hillion, Melanie; Huang, Jingjing; Ilikay, Serap; Jansen-Dürr, Pidder; Jaquet, Vincent; Joles, Jaap A; Kalyanaraman, Balaraman; Kaminskyy, Danylo; Karbaschi, Mahsa; Kleanthous, Marina; Klotz, Lars-Oliver; Korac, Bato; Korkmaz, Kemal Sami; Koziel, Rafal; Kračun, Damir; Krause, Karl-Heinz; Kren, Vladimir ; Krieg, Thomas; Laranjinha, João ; Lazou, Antigone; Li, Huige; Martínez-Ruiz, Antonio; Matsui, Reiko; McBean, Gethin J.; Meredith, Stuart P.; Messens, Joris; Miguel, Verónica; Mikhed, Yuliya; Milisav, Irina; Milković, Lidija; Miranda-Vizuete, Antonio; Mojović, Miloš; Monsalve, María; Mouthuy, Pierre-Alexis; Mulvey, John; Münzel, Thomas; Muzykantov, Vladimir; Nguyen, Isabel T. N.; Oelze, Matthias; Oliveira, Nuno G; Palmeira, Carlos M. ; Papaevgeniou, Nikoletta; Pavićević, Aleksandra; Pedre, Brandán; Peyrot, Fabienne; Phylactides, Marios; Pircalabioru, Gratiela G.; Pitt, Andrew R.; Poulsen, Henrik E.; Prieto, Ignacio; Rigobello, Maria Pia; Robledinos-Antón, Natalia; Rodríguez-Mañas, Leocadio; Rolo, Anabela P. ; Rousset, Francis; Ruskovska, Tatjana; Saraiva, Nuno ; Sasson, Shlomo; Schröder, Katrin; Semen, Khrystyna; Seredenina, Tamara; Shakirzyanova, Anastasia; Smith, Geoffrey L.; Soldati, Thierry; Sousa, Bebiana C.; Spickett, Corinne M.; Stancic, Ana; Stasia, Marie José; Steinbrenner, Holger; Stepanić, Višnja; Steven, Sebastian; Tokatlidis, Kostas; Tuncay, Erkan; Turan, Belma; Ursini, Fulvio; Vacek, Jan; Vajnerova, Olga; Valentová, Kateřina; Van Breusegem, Frank; Varisli, Lokman; Veal, Elizabeth A.; Yalçın, A Suha; Yelisyeyeva, Olha; Žarković, Neven; Zatloukalová, Martina; Zielonka, Jacek; Touyz, Rhian M.; Papapetropoulos, Andreas; Grune, Tilman; Lamas, Santiago; Schmidt, Harald H H W; Di Lisa, Fabio; Daiber, AndreasarticleopenAccess
92013High-Resolution Respirometry for Metabolic Profiling of Acute Rat Hippocampal SlicesHenriques, Tiago André Ferreira masterThesisopenAccess
10Dec-2013Human colon adenocarcinoma HT-29 cell: electrochemistry and nicotine stimulationOliveira, S. C. B. ; Santarino, I. B. ; Enache, T. A. ; Nunes, C. ; Laranjinha, J. ; Barbosa, R. M. ; Brett, A. M. Oliveira articleopenAccess
1124-Sep-2018Innovative pathways underlying the etiology and the therapeutics via modulation of the gut microbiotaRibeiro, Ricardo Manuel EstevesmasterThesisopenAccess
1225-Sep-2020Internship report and thesis entitled “Diet, microbiota and epigenetics – a dynamic and adjustable triade to explore new treatment approaches”Reva, KaterinamasterThesisopenAccess
1326-Sep-2017O microbiota e o ser humanoQueiroz, João Pedro Nunes masterThesisopenAccess
146-Nov-2017Microbiota-host interactions during antibiotic therapy: unveiling novel redox signaling pathways with impact on gut homeostasisRocha, Bárbara Silva masterThesisclosedAccess
1528-Jul-2017Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arraysLourenço, Cátia F. ; Ledo, Ana ; Gerhardt, Greg A. ; Laranjinha, João ; Barbosa, Rui M. articleopenAccess
162015Neurovascular and neurometabolic derailment in aging and Alzheimer's diseaseLourenço, Cátia F. ; Ledo, Ana ; Dias, Cândida ; Barbosa, Rui M. ; Laranjinha, João articleopenAccess
172012Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegenerationSantos, Ricardo M. ; Lourenço, Cátia F. ; Ledo, Ana ; Barbosa, Rui M. ; Laranjinha, João articleopenAccess
182012Nitric oxide mediates neurovascular coupling in the brain effect of polyphenols in animal models of Alzheimer's diseaseFonseca, Ana rita de Jesus Alves da masterThesisopenAccess
19Sep-2016Nutrigenómica e qualidade de vida : funções e eficácia de moduladores de NRF2 presentes em suplementos da dietaOliveira, Luís Francisco Lourenço Vaz deotheropenAccess
20Jul-2014Obesidade e diabetes: o papel das citocinas do tecido adiposoMoura, Pedro Miguel Cruz HenriquesotheropenAccess
2126-Jun-2019Pathophysiology of Doxorubicin Cardiotoxicity: From Mitochondrial Homeostasis to Biological ClocksFerreira, Luciana Carolina LopesdoctoralThesisembargoedAccess
223-Oct-2017Relatório de estágio e monografia intitulada :"mecanismos epigenéticos na formação de memória e capacidades cognitivas"Brazão, João António Lima de Andrade CondemasterThesisopenAccess
2314-Sep-2018Relatórios de Estágio e Monografia intitulada “Novas Estratégias Biomédicas: Modulação do Epigenoma e Terapia do Cancro"Arrais, Débora Gomes masterThesisopenAccess
243-Oct-2017Relatórios de Estágio e Monografia intitulada “O Parkinson, a Microbiota Intestinal e a Epigenética”Silva, Miguel Pereira da masterThesisopenAccess
25Aug-2016Role of nitrite, urate and pepsin in the gastroprotective effects of salivaRocha, Bárbara S. ; Lundberg, Jon O. ; Radi, Rafael; Laranjinha, João articleopenAccess
26Feb-2013Self-mixing microprobe for monitoring microvascular perfusion in rat brainFigueiras, Edite ; Oliveira, Ricardo ; Lourenço, Cátia F. ; Campos, Rita ; Humeau-Heurtier, Anne ; Barbosa, Rui M. ; Laranjinha, João ; Requicha Ferreira, Luís F. ; de Mul, Frits F M articleopenAccess
27Jul-2016Síndrome metabólico e dieta vegetariana: relação benéfica, deletéria ou irrelevante?Lijnzaat, Pedro de AzevedootheropenAccess
28Jul-2016The human microbiome: a fine line between symbiosis and pathogenesisGonçalves, João Miguel da SilvaotheropenAccess
291-Apr-2016The interplay of ascorbic acid, nitric oxide and nitrite in the brain and its role on the regulation of cerebral blood flow: an in vivo electrochemical studyFerreira, Nuno Ricardo Esteves doctoralThesisopenAccess
30Sep-2016The long and winding road of STAT3 in the mitochondriaRamos, Carlos Eduardo Cardanho dosotheropenAccess
31Jul-2016The pathogenesis of Parkinson Disease : the microbiota-gut-brain axisFernandes, Ana Rita CardosootheropenAccess
329-May-2013The redox interplay between nitrite and nitric oxide: From the gut to the brainPereira, Cassilda ; Ferreira, Nuno R. ; Rocha, Bárbara S. ; Barbosa, Rui M. ; Laranjinha, João articleopenAccess
3318-May-2016The role of nitrite-derived nitric oxide in gastric physiology: biochemical mechanisms, molecular targets and the modulatory effect of red winePereira, Cassilda Maria Lopes doctoralThesisopenAccess
342011The role of polyphenols and reactive nitrogen species in inflammatory conditions of the gastrointestinal tract|Ferreira, Elisabete Priscila Pinto masterThesisopenAccess
3518-Jan-2013Unravelling New Roles for SIRT1 in Mitochondrial BiollogyGomes, Ana Patrícia da Silva doctoralThesisopenAccess