Ramalho-Santos, João
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Credit Name
Ramalho-Santos, João
Name
Santos, João Ramalho
Unidade de I&D
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Researcher ID
Status
UC Researcher
Biography
João Ramalho-Santos is Professor at the Department of Life Sciences, University of Coimbra, Portugal, where he concluded his Ph.D in Cell Biology in 1997. He was a post-doctoral fellow in Reproductive Biology at Oregon Health & Science University USA (1997-2000), a Visiting Scientist at University of Pittsburgh, USA (2003-2006) and a Fulbright Fellow at University of California San Francisco, USA (2009). He currently is the Head of the Biology of Reproduction and Stem Cells Group at the Center for Neuroscience and Cell Biology at the University of Coimbra where he works on the bioenergetics and metabolism of gametes and stem cells, and on Science Communication and Bioethics issues related both to Assisted Reproduction and metabolism, aging and disease.
He is also Director of the Center for Neuroscience and Cell Biology.
He is Associate Editor of the Journals Reproduction and Human Reproduction, reviewer for over 30 journals and 6 agencies (Including FCT, Portugal, MRC, UK, and DFG, Germany). He is a former member of the National Ethics Council for the Life Sciences (CNECV)
h-Factor 47 (Google Scholar), 38 (ISI)
Citations: 8500 (Google Scholar), 5100 (ISI)
He is also Director of the Center for Neuroscience and Cell Biology.
He is Associate Editor of the Journals Reproduction and Human Reproduction, reviewer for over 30 journals and 6 agencies (Including FCT, Portugal, MRC, UK, and DFG, Germany). He is a former member of the National Ethics Council for the Life Sciences (CNECV)
h-Factor 47 (Google Scholar), 38 (ISI)
Citations: 8500 (Google Scholar), 5100 (ISI)
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Results 1-69 of 69 (Search time: 0.002 seconds).
Issue Date | Title | Author(s) | Type | Access | |
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1 | 2001 | Acrosome components after intracytoplasmic sperm injection: the decondensation frontier | Ramalho-Santos, João ; Simerly, Calvin R. ; Hewitson, Laura ; Schatten, Gerald | article | openAccess |
2 | 2012 | Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial function | Mota, Paula C. ; Tavares, Renata S. ; Cordeiro, Marília ; Pereira, Susana P. ; Publicover, Stephen J. ; Oliveira, Paulo J. ; Ramalho-Santos, João | article | openAccess |
3 | 2008 | Adição de piruvato de sódio e trolox ao diluidor utilizado para congelação de sêmen de garanhões férteis e subférteis | Silva, Karen Mascaro Gonçalves da; Gamboa, Sandra Cristina de Oliveira Pinto ; Rodrigues, Ana Sofia ; Santos, João Ramalho ; Guerra, Maria Madalena Pessoa | article | openAccess |
4 | 2013 | Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengths | Alçada-Morais, Sofia ; Sousa, Ana Paula ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, J. | article | openAccess |
5 | 16-Aug-2019 | Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease | Fontes, Adriana ; Alemany-Pagès, Mireia; Oliveira, Paulo J. ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa | article | openAccess |
6 | 2018 | Bridging Health and Social Care with the Citizens – The Case of EIT Health Project “Healiqs4cities” and “Praça Vida+”, in Portugal | Sá-Moura, Bebiana ; Couceiro, Patrícia ; Catarino, Luis ; Guardado, Diana; Brito, Maja de ; Silva, Bárbara ; Tavares, Rui ; Ramalho-Santos, João ; Teixeira, Ana M. ; Rama, Luís ; Reis, Flávio ; Mota-Pinto, Anabela ; Veríssimo, Manuel ; Gonçalves, Carlos ; Cunha, António ; Malva, João O. | article | openAccess |
7 | 2018 | Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach? | Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. | article | openAccess |
8 | 2007 | Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers | Varum, Sandra ; Bento, Carla ; Sousa, Ana Paula M. ; Gomes-Santos, Carina S. S. ; Henriques, Paula ; Almeida-Santos, Teresa ; Teodósio, Cristina ; Paiva, Artur ; Ramalho-Santos, João | article | openAccess |
9 | 2023 | Comics in Science and Health Communication: Insights From Mutual Collaboration and Framing a Research Practice | Tavares, Rui ; Alemany-Pagès, Mireia; Araújo, Sara ; Cohn, Neil; Santos, João Ramalho ; Azul, Anabela Marisa | article | openAccess |
10 | Mar-1993 | A common mechanism for influenza virus fusion activity and inactivation | Ramalho-Santos, João ; Nir, Shlomo ; Düzgünes, Nejat ; Carvalho, Arsélio Pato de ; Lima, Maria da Conceição Pedroso de | article | openAccess |
11 | 2006 | Comparison between different markers for sperm quality in the cat: Diff-Quik as a simple optical technique to assess changes in the DNA of feline epididymal sperm | Mota, Paula C. ; Ramalho-Santos, João | article | openAccess |
12 | Jun-2016 | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells | Correia, Marcelo ; Sousa, Maria I. ; Rodrigues, Ana S. ; Perestrelo, Tânia ; Pereira, Sandro L.; Ribeiro, Marcelo F.; Ramalho-Santos, João | article | openAccess |
13 | 2015 | Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency | Rodrigues, Ana Sofia ; Correia, Marcelo ; Gomes, Andreia ; Pereira, Sandro L. ; Perestrelo, Tânia ; Sousa, Maria Inês ; Ramalho-Santos, João | article | openAccess |
14 | Jan-2011 | Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicology | Mota, Paula C. ; Cordeiro, Marília ; Pereira, Susana P. ; Oliveira, Paulo J. ; Moreno, António J. ; Ramalho-Santos, João | article | openAccess |
15 | 29-Mar-2022 | Differential Oxygen Exposure Modulates Mesenchymal Stem Cell Metabolism and Proliferation through mTOR Signaling | Moniz, Inês ; Ramalho-Santos, João ; Branco, Ana F. | article | openAccess |
16 | 2015 | Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells | Rodrigues, Ana Sofia ; Pereira, Sandro L. ; Correia, Marcelo ; Gomes, Andreia M. ; Perestrelo, Tânia ; Ramalho-Santos, João | article | openAccess |
17 | 2013 | Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats | Pereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, J. ; Moreno, A. J. M. ; Oliveira, Paulo J. | article | openAccess |
18 | 2009 | Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sperm morphology and chromatin status | Sousa, Ana Paula M. ; Tavares, Renata S. ; Velez de la Calle, Juan Felipe ; Figueiredo, Helena ; Almeida, Vasco ; Almeida-Santos, Teresa ; Ramalho-Santos, João | article | openAccess |
19 | 2020 | Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs) | Sousa, Maria Inês ; Correia, Bibiana ; Branco, Ana Filipa ; Rodrigues, Ana Sofia ; Ramalho-Santos, João | article | openAccess |
20 | 2006 | Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes | Amaral, Sandra ; Moreno, António J. ; Santos, Maria Sancha ; Seiça, Raquel ; Ramalho-Santos, João | article | openAccess |
21 | 17-Jun-2011 | Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts | Varum, Sandra ; Rodrigues, Ana S. ; Moura, Michelle B. ; Momcilovic, Olga ; Easley, Charles A. ; Ramalho-Santos, João ; Van Houten, Bennett ; Schatten, Gerald | article | openAccess |
22 | 2013 | Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilization | Tavares, R. S. ; Silva, A. F. ; Lourenço, B. ; Almeida-Santos, T. ; Sousa, A. P. ; Ramalho-Santos, J. | article | openAccess |
23 | 2006 | Flow cytometry evaluation of lead and cadmium effects on mouse spermatogenesis | Oliveira, Helena ; Loureiro, João ; Filipe, Luísa ; Santos, Conceição ; Ramalho-Santos, João ; Sousa, Mário ; Pereira, Maria de Lourdes | article | openAccess |
24 | 2002 | Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliability | Nunes-Correia, Isabel ; Eulálio, Ana ; Nir, Shlomo ; Düzgünes, Nejat ; Ramalho-Santos, João ; Lima, Maria C. Pedroso de | article | openAccess |
25 | 2020 | Fluorescent probes for the detection of reactive oxygen species in human spermatozoa | Escada-Rebelo, Sara ; Mora, Francisca ; Sousa, Ana ; Almeida Santos, Teresa ; Paiva, Artur ; Ramalho-Santos, João | article | openAccess |
26 | 2008 | Freeze-dried primate sperm retains early reproductive potential after intracytoplasmic sperm injection | Sánchez-Partida, Luis Gabriel ; Simerly, Calvin R. ; Ramalho-Santos, João | article | openAccess |
27 | 2001 | Fusion and Infection of Influenza and Sendai Viruses as Modulated by Dextran Sulfate: A Comparative Study | Ramalho-Santos, João ; Lima, Maria Pedroso de | article | openAccess |
28 | May-2002 | Golgi apparatus dynamics during mouse oocyte in vitro maturation: effect of the membrane trafficking inhibitor brefeldin A | Moreno, Ricardo D. ; Schatten, Gerald ; Ramalho-Santos, João | article | openAccess |
29 | 2006 | Histopathological Effects of Hexavalent Chronium in Mouse Kidney | Oliveira, H. ; Santos, T. M. ; Ramalho-Santos, J. ; Pereira, M. de Lourdes | article | openAccess |
30 | 2015 | I Want More and Better Cells! - An Outreach Project about Stem Cells and Its Impact on the General Population | Amaral, Sara Varela ; Forte, Teresa ; Ramalho-Santos, João ; Cruz, M. Teresa Girão da | article | openAccess |
31 | 10-May-2023 | In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration | Pereira, Patrícia ; Neto, Ana S.; Rodrigues, Ana Sofia ; Barros, Inês ; Miranda, Catarina O. ; Santos, João Ramalho ; Almeida, Luís Pereira de ; Ferreira, José M. F.; Coelho, Jorge ; Fonseca, Ana C. | article | openAccess |
32 | 16-May-2011 | In Vitro Surfactant Structure-Toxicity Relationships: Implications for Surfactant Use in Sexually Transmitted Infection Prophylaxis and Contraception | Inácio, Ângela S. ; Mesquita, Katia A. ; Baptista, Marta ; Ramalho-Santos, João ; Vaz, Winchil L. C. ; Vieira, Otília V. | article | openAccess |
33 | 1998 | The influenza virus hemagglutinin: a model protein in the study of membrane fusion | Ramalho-Santos, João ; Pedroso de Lima, Maria C. | article | openAccess |
34 | 2-Dec-2013 | Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell Pluripotency | Sandro, L. Pereira ; Grãos, Mário ; Rodrigues, Ana Sofia ; Anjo, Sandra I. ; Carvalho, Rui A. ; Oliveira, Paulo J. ; Arenas, Ernest ; Ramalho-Santos, João | article | openAccess |
35 | 20-Jul-2020 | Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance? | Alemany-Pagès, Mireia; Moura-Ramos, Mariana ; Araújo, Sara ; Macedo, Maria Paula ; Ribeiro, Rogério T. ; do Ó, Dulce; Santos, João Ramalho ; Azul, Anabela Marisa | article | openAccess |
36 | 19-Jan-1999 | Interactions of Influenza Virus with Cultured Cells: Detailed Kinetic Modeling of Binding and Endocytosis | Nunes-Correia, Isabel ; Ramalho-Santos, João ; Nir, Shlomo ; Lima, Maria C. Pedroso de | article | openAccess |
37 | 2-Feb-2023 | Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation | Soares, Maria ; Pinto, Maria M. ; Nobre, Rui J. ; Almeida, Luís Pereira de ; Rasteiro, Maria da Graça ; Santos, Teresa Almeida ; Santos, João Ramalho ; Sousa, Ana Paula | article | openAccess |
38 | 1992 | Kinetic modeling of Sendai virus fusion with PC-12 cells. Effect of pH and temperature on fusion and viral inactivation | Lima, Maria da Conceição Pedroso de ; Ramalho-Santos, João ; Martins, Maria de Fátima ; Carvalho, Arsélio Pato de ; Bairos, Vasco ; Nir, Shlomo | article | openAccess |
39 | 2003 | LIS1 association with dynactin is required for nuclear motility and genomic union in the fertilized mammalian oocyte | Payne, Christopher ; John, Justin C. St. ; Ramalho-Santos, João ; Schatten, Gerald | article | openAccess |
40 | 2001 | Membrane Trafficking Machinery Components Associated with the Mammalian Acrosome during Spermiogenesis | Ramalho-Santos, João ; Moreno, Ricardo D. ; Wessel, Gary M. ; Chan, Edward K. L. ; Schatten, Gerald | article | openAccess |
41 | 2013 | Mitochondria and mammalian reproduction | Ramalho-Santos, J. ; Amaral, Sandra | article | openAccess |
42 | Jun-2023 | Mitochondria as biological targets for stem cell and organismal senescence | Branco, Ana ; Moniz, Inês ; Santos, João Ramalho | article | openAccess |
43 | 2013 | Mitochondria functionality and sperm quality | Amaral, Alexandra ; Lourenço, Bárbara ; Marques, Mónica ; Ramalho-Santos, J. | article | openAccess |
44 | 30-Apr-2009 | Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)--A model for endangered species | Mota, Paula ; Amaral, Sandra ; Martins, Luís ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João | article | openAccess |
45 | Mar-2004 | Mouse genetic corneal disease resulting from transgenic insertional mutagenesis | Ramalho, J. S. ; Gregory-Evans, K. ; Huxley, C. ; Seabra, M. C. | article | openAccess |
46 | Mar-2022 | Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets | Fontes, Adriana ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa de Jesus Rodrigues | article | openAccess |
47 | 27-Sep-2023 | New Insights on Sperm Function in Male Infertility of Unknown Origin: A Multimodal Approach | Pacheco, Rita I. ; Cristo, Maria I. ; Anjo, Sandra I. ; Silva, Andreia F. ; Sousa, Maria Inês ; Santos Tavares, Renata ; Sousa, Ana Paula ; Santos, Teresa Almeida ; Moura-Ramos, Mariana ; Caramelo, Francisco ; Manadas, Bruno ; Santos, João Ramalho ; Amaral, Sandra Gomes | article | openAccess |
48 | 23-Mar-2011 | Not All Sperm Are Equal: Functional Mitochondria Characterize a Subpopulation of Human Sperm with Better Fertilization Potential | Sousa, Ana Paula ; Amaral, Alexandra ; Baptista, Marta ; Tavares, Renata ; Caballero Campo, Pedro ; Caballero Peregrín, Pedro ; Freitas, Albertina ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, João | article | openAccess |
49 | 2013 | p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations | Tavares, Renata S. ; Mansell, Steven ; Barratt, Christopher L. R. ; Wilson, Stuart M. ; Publicover, Stephen J. ; Ramalho-Santos, João | article | openAccess |
50 | 2009 | Parabens in male infertility--Is there a mitochondrial connection? | Tavares, Renata S. ; Martins, Fátima C. ; Oliveira, Paulo J. ; Ramalho-Santos, João ; Peixoto, Francisco P. | article | openAccess |
51 | 27-Sep-1996 | Partial fusion activity of influenza virus toward liposomes and erythrocyte ghosts is distinct from viral inactivation | Ramalho-Santos, João ; Lima, Maria C. Pedroso de ; Nir, Shlomo | article | openAccess |
52 | 8-Aug-2017 | Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software | Perestrelo, Tânia ; Chen, Weitong; Correia, Marcelo ; Le, Christopher; Pereira, Sandro ; Rodrigues, Ana S. ; Sousa, Maria I. ; Ramalho-Santos, João ; Wirtz, Denis | article | openAccess |
53 | May-2020 | Publicly stressing the role of mitochondria in NAFLD with(in) a sports event | Alemany-Pagès, Mireia; Tavares, Rui Miguel dos Santos ; Varela Amaral, Sara; Barros-Viegas, Ana Teresa ; Oliveira, Paulo J. ; Santos, João Ramalho de Sousa ; Azul, Anabela Marisa de Jesus Rodrigues | article | embargoedAccess |
54 | 2008 | The quantification of lipid and protein oxidation in stallion spermatozoa and seminal plasma: Seasonal distinctions and correlations with DNA strand breaks, classical seminal parameters and stallion fertility | Morte, Maria Inês ; Rodrigues, Ana Margarida ; Soares, Diana ; Rodrigues, Ana Sofia ; Gamboa, Sandra ; Ramalho-Santos, João | article | openAccess |
55 | 16-Mar-1999 | Role of a Transbilayer pH Gradient in the Membrane Fusion Activity of the Influenza Virus Hemagglutinin: Use of the R18 Assay to Monitor Membrane Merging | Ramalho-Santos, João ; Lima, Maria C. Pedroso de | article | openAccess |
56 | 2004 | The role of target membrane sialic acid residues in the fusion activity of the influenza virus: the effect of two types of ganglioside on the kinetics of membrane merging | Ramalho-Santos, João ; Lima, Maria C. Pedroso de | article | openAccess |
57 | 1-Sep-2008 | Seminal traits, suitability for semen preservation and fertility in the native Portuguese horse breeds Puro Sangue Lusitano and Sorraia: Implications for stallion classification and assisted reproduction | Gamboa, Sandra ; Machado-Faria, Manuel ; Ramalho-Santos, João | article | openAccess |
58 | 1998 | Sendai Virus Fusion Activity as Modulated by Target Membrane Components | Nunes-Correia, Isabel ; Ramalho-Santos, João ; Pedroso de Lima, Maria C. | article | openAccess |
59 | 2004 | Simultaneous analysis of cytoskeletal patterns and chromosome positioning in human fertilization failures | Ramalho-Santos, João ; Amaral, Alexandra ; Brito, Raquel ; Freitas, Mariana ; Santos, Teresa Almeida | article | openAccess |
60 | 2005 | SNARE proteins and caveolin-1 in stallion spermatozoa: possible implications for fertility | Gamboa, Sandra ; Ramalho-Santos, João | article | openAccess |
61 | 2000 | SNAREs in Mammalian Sperm: Possible Implications for Fertilization | Ramalho-Santos, João ; Moreno, Ricardo D. ; Sutovsky, Peter ; Chan, Anthony Wing-Sang ; Hewitson, Laura ; Wessel, Gary M. ; Simerly, Calvin R. ; Schatten, Gerald | article | openAccess |
62 | Aug-2008 | Surfactants as microbicides and contraceptive agents: a systematic in vitro study | Vieira, Otília V. ; Hartmann, Diego O. ; Cardoso, Carla M. P. ; Oberdoerfer, Daniel ; Baptista, Marta ; Santos, Manuel A. S. ; Almeida, Luis ; Ramalho-Santos, João: | article | openAccess |
63 | 2008 | Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak | Amaral, Sandra ; Mota, Paula ; Rodrigues, Ana Sofia ; Martins, Luís ; Oliveira, Paulo J. ; Ramalho-Santos, João | article | openAccess |
64 | 2009 | Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats | Amaral, Sandra ; Mota, Paula C. ; Lacerda, Beatriz ; Alves, Marco ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João | article | openAccess |
65 | 6-Sep-2021 | Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study | Azul, Anabela Marisa ; Almendra, Ricardo ; Quatorze, Marta; Loureiro, Adriana ; Reis, Flávio ; Tavares, Rui ; Mota-Pinto, Anabela ; Cunha, António ; Rama, Luís ; Malva, João Oliveira ; Santana, Paula ; Santos, João Ramalho ; HeaLIQs4Cities, consortium | article | openAccess |
66 | 9-Aug-2021 | Using Data Mining to Assist in Predicting Reproductive Outcomes Following Varicocele Embolization | Sousa, Ana Paula ; Santos-Pereira, Judith; Freire, Maria José; Parada, Belmiro ; Almeida Santos, Teresa ; Bernardino, Jorge; Ramalho-Santos, João | article | openAccess |
67 | 2013 | UVB irradiation as a tool to assess ROS-induced damage in human spermatozoa | Amaral, S. ; Redmann, K. ; Sanchez, V. ; Mallidis, C. ; Ramalho-Santos, J. ; Schlatt, S. | article | openAccess |
68 | 2002 | VAMP/synaptobrevin as an acrosomal marker for human sperm | Ramalho-Santos, João ; Terada, Yukihiro ; Schatten, Gerald | article | openAccess |
69 | 2-Sep-2010 | Xenografting as a tool to preserve endangered species: outcomes and challenges in model systems | Mota, Paula C. ; Ramalho-Santos, João ; Schlatt, Stefan | article | openAccess |
Projects
(Principal Investigator)
Results 1-1 of 1 (Search time: 0.0 seconds).
Title | P-Investigator |
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Foie Gras: Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease | Santos, João Ramalho |