This work was supported by AIRC (Associazione Italiana per la Ricerca sul Cancro) Special Program “Innovative Tools for Cancer Risk Assessment and early Diagnosis”, 5X1000 (no. 12162) to L.R., D.D., U.P., and G.S. and IG16847 (to L.R.). Mi.M. was supported by the FIRB RBAP11Z4Z9 project from the Italian Ministry of Education, University and Research.