The authors thank Coimbra Chemistry Centre (CQC), supported by the Portuguese Agency for Scientific Research, “Fundaç~ao para a Ci^encia e a Tecnologia” (FCT) through project UIDB/00313/2020 and UIDP/00313/2020, co-funded by COMPETE2020-UE. iMed. ULisboa, Faculdade de Farm acia de Lisboa, Portugal, is supported by FCT through Projects UIDB/04138/2020 and UIDP/04138/2020, cofunded by COMPETE2020-UE. Miguel Prud^encio acknowledges FCT for grant PTDC/SAU-INF/29550/2017. Nuno Guerreiro Alves and Am erico J. S. Alves thank FCT for fellowships PD/BD/135287/2017 and SFRH/BD/128910/2017, respectively.