Supported by the European Regional Development Fund through the Regional Operational Program Center 2020, Competitiveness Factors Operational Program (COMPETE 2020) and National Funds through Foundation for Science and Technology (FCT): UID/NEU/04539/2020, BrainHealth2020 projects (CENTRO-01-0145- FEDER-000008), ViraVector (CENTRO-01-0145-FEDER-022095), CortaCAGs (POCI-01-0145-FEDER-016719), SpreadSilencing POCI-01-0145-FEDER-029716, CancelStem (POCI-01-0145-FEDER-016390), and the SynSpread, European SCA3/MJD Initiative and ModelPolyQ under the EU Joint Program, the last two co-funded by the European Union H2020 program, GA No. 643417; by the National Ataxia Foundation, the American Portuguese Biomedical Research Fund and the Richard Chin and Lily Lock Machado–Joseph Disease Research Fund.

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Supported by the European Regional Development Fund through the Regional Operational Program Center 2020, Competitiveness Factors Operational Program (COMPETE 2020) and National Funds through Foundation for Science and Technology (FCT): UID/NEU/04539/2020, BrainHealth2020 projects (CENTRO-01-0145- FEDER-000008), ViraVector (CENTRO-01-0145-FEDER-022095), CortaCAGs (POCI-01-0145-FEDER-016719), SpreadSilencing POCI-01-0145-FEDER-029716, CancelStem (POCI-01-0145-FEDER-016390), and the SynSpread, European SCA3/MJD Initiative and ModelPolyQ under the EU Joint Program, the last two co-funded by the European Union H2020 program, GA No. 643417; by the National Ataxia Foundation, the American Portuguese Biomedical Research Fund and the Richard Chin and Lily Lock Machado–Joseph Disease Research Fund.