Browsing by Author Brito, Rui M. M.


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Issue DateTitleAuthor(s)TypeAccess
19-Apr-2022Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine HydroxylaseConde-Giménez, María; Galano-Frutos, Juan José; Galiana-Cameo, María; Mahía, Alejandro; Victor, Bruno L. ; Salillas, Sandra; Velázquez-Campoy, Adrián; Brito, Rui M. M. ; Gálvez, José Antonio; Díaz-de-Villegas, María D.; Sancho, JavierarticleopenAccess
2020An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site DissimilaritiesAlves, Nuno G. ; Mata, Ana I. ; Luís, João P. ; Brito, Rui M. M. ; Simões, Carlos J. V. articleopenAccess
2016Cell Spotting: educational and motivational outcomes of cell biology citizen science project in the classroomBrito, Rui M. M. ; Carrodeguas, Jose; Serrano Sanz, Fermin; Mota, Paulo ; Brasileiro, Francisco; Andrade, Nazareno; Schäfer, Teresa; Lostal, Eduardo; Manahl, Caroline; Monteiro, Antonio; Silva, Cândida G. articleopenAccess
2012Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channelHarley, Carol A.; Jesus, Catarina S. H. ; Carvalho, Ricardo; Brito, Rui M. M. ; Morais-Cabral, João H.articleopenAccess
Sep-2010Cinética de agregação da proteína transtirretina: contribuição para a compreensão dos processos de formação de amilóideAlmeida, Zaida C. Lourenço de masterThesisopenAccess
2000Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretinShnyrov, Valery L. ; Villar, Enrique ; Zhadan, Galina G. ; Sanchez-Ruiz, Jose M. ; Quintas, Alexandre ; Saraiva, Maria João M. ; Brito, Rui M. M. articleopenAccess
26-Feb-2022Conformational Dynamics of the Soluble and Membrane-Bound Forms of Interleukin-1 Receptor Type-1: Insights into Linker Flexibility and Domain OrientationLuís, João P. ; Mata, Ana I. ; Simões, Carlos J. V. ; Brito, Rui M. M. articleopenAccess
Feb-2016Em busca de determinantes estruturais no reconhecimento e ligação de amilóide: β-2 microglobulina como caso de estudoFernandes, Pedro Miguel Pinto masterThesisopenAccess
2012Uma estratégia para a discriminação entre compostos activos e inactivos em experiências de rastreio virtual : COX-1 como caso de estudoCarreiras, Pedro Miguel Serrano Germano Calado masterThesisopenAccess
27-Sep-2017Estudo das alterações metabólicas post mortem no fígado por espectroscopia de RMNTomé, Ana Sofia Monteiro masterThesisopenAccess
2016Hereditary nonspherocytic hemolytic anemia caused by red cell glucose-6-phosphate isomerase (GPI) deficiency in two Portuguese patients: Clinical features and molecular studyManco, Licínio ; Bento, Celeste ; Victor, Bruno L. ; Pereira, Janet ; Relvas, Luís ; Brito, Rui M. ; Seabra, Carlos ; Maia, Tabita M. ; Ribeiro, M. Letícia articleopenAccess
Sep-2015Identification and characterization of small molecule interactions with transthyretin amyloid fibersFerreira, Elisabete Priscila Pinto masterThesisopenAccess
31-Jan-2014Kinetics and Energetics of Fundamental Events in Peptide and Protein (Un)FoldingJesus, Catarina Sofia Henriques de doctoralThesisembargoedAccess
14-Nov-2020Ligand-Targeted Delivery of Photosensitizers for Cancer TreatmentGierlich, Piotr ; Mata, Ana I. ; Donohoe, Claire ; Brito, Rui M. M. ; Senge, Mathias O. ; Silva, Lígia C. Gomes da articleopenAccess
31-Aug-2016A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M MutationJesus, Catarina S. H. ; Almeida, Zaida L. ; Vaz, Daniela C. ; Faria, Tiago Q. ; Brito, Rui M. M. articleopenAccess
3-Dec-2020Oligomerization Profile of Human Transthyretin Variants with Distinct AmyloidogenicityFrangolho, Ana; Correia, Bruno E.; Vaz, Daniela C. ; Almeida, Zaida L. ; Brito, Rui M. M. articleopenAccess
26-Sep-2019OSA and TransthyretinSantos, Alexander Michael RibeiromasterThesisembargoedAccess
25-Sep-2019O papel dos halogénios no desenho de fármacos. O caso da ligação de pequenos ligantes à Transtirretina.Caniceiro, Ana Beatriz Ramos masterThesisopenAccess
15-Nov-2010Protein conformational plasticity and aggregation : transthyretin and δ-toxin as two case studiesFerreira, Nuno Ricardo Santos Loureiro da Silva doctoralThesisopenAccess
30-Dec-2021Searching for the Best Transthyretin Aggregation Protocol to Study Amyloid Fibril DisruptionFerreira, Elisabete ; Almeida, Zaida L. ; Cruz, Pedro F. ; Sousa, Marta Silva e ; Veríssimo, Paula ; Brito, Rui M. M. articleopenAccess